Evidence map›Paper›PMID 35233480›Full record

ArticleRheumatology advances in practice2022

Persistent post-discharge symptoms after COVID-19 in rheumatic and musculoskeletal diseases.

Leticia Leon, Ines Perez-Sancristobal, Alfredo Madrid, Leticia Lopez-Pedraza, Jose Ignacio Colomer, Sergio Lerma, Pia Lois, Arkaitz Mucientes, Luis Rodriguez-Rodriguez, Benjamin Fernandez-Gutierrez and 1 more

Open access · goldAbstract read
In one paragraph

Article in Rheumatology advances in practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  12. [COVID 19 - Some lessons and many more to learn].Revista colombiana de reumatologia
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Leticia LeonRheumatology Department and IdISSC, Hospital Clinico San Carlos.ORCID https://orcid.org/0000-0001-7142-0545
Ines Perez-SancristobalRheumatology Department and IdISSC, Hospital Clinico San Carlos.
Alfredo MadridRheumatology Department and IdISSC, Hospital Clinico San Carlos.
Leticia Lopez-PedrazaRheumatology Department and IdISSC, Hospital Clinico San Carlos.
Jose Ignacio ColomerRheumatology Department and IdISSC, Hospital Clinico San Carlos.
Sergio LermaHealth Sciences Faculty, Physical Therapy Department, Centro Superior de Estudios universitarios La Salle, Universidad Autonoma de Madrid, Madrid, Spain.
Pia LoisRheumatology Department and IdISSC, Hospital Clinico San Carlos.
Arkaitz MucientesRheumatology Department and IdISSC, Hospital Clinico San Carlos.
Luis Rodriguez-RodriguezRheumatology Department and IdISSC, Hospital Clinico San Carlos.ORCID https://orcid.org/0000-0002-2869-7861
Benjamin Fernandez-GutierrezRheumatology Department and IdISSC, Hospital Clinico San Carlos.
Lydia AbasoloRheumatology Department and IdISSC, Hospital Clinico San Carlos.
Hospital Clínico San Carlos · ESUniversidad Autónoma de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to describe persistent symptoms and sequelae in patients with rheumatic and musculoskeletal diseases (RMD) after admission owing to coronavirus disease 2019 (COVID-19), assessing the role of autoimmune rheumatic diseases (ARDs) compared with non-autoimmune rheumatic and musculoskeletal diseases (NARDs) on persistent symptoms and sequelae.

methodsWe performed an observational study including RMD patients who attended a rheumatology clinic in Madrid and required admission owing to COVID-19 (between March and May 2020) and survived. The study began at discharge and ran until October 2020. Main outcomes were persistence of symptoms and sequelae related to COVID-19. The independent variable was the RMD group (ARD and NARD). Covariates included sociodemographics, clinical and treatment data. We ran a multivariate logistic regression model to assess the risk of the main outcomes by RMD group.

resultsWe included 105 patients, of whom 51.5% had ARD and 68.57% reported at least one persistent symptom. The most frequent symptoms were dyspnoea, fatigue and chest pain. Sequelae were recorded in 31 patients. These included lung damage in 10.4% of patients, lymphopenia in 10%, a central retinal vein occlusion and an optic neuritis. Two patients died. Eleven patients required re-admission owing to COVID-19 problems (16.7% ARD

conclusionMany RMD patients have persistent symptoms, as in other populations. Lung damage is the most frequent sequela. Compared with NARD, ARD does not seem to differ in terms of persistent symptoms or consequences, although ARD might have more re-admissions owing to COVID-19.

Indexed as

autoimmune diseasesCOVID-19post-acute COVID-19 syndromepost-acute sequelaerheumatic diseasesSARS-CoV-2 infection

Identifiers

PMID35233480
PMCPMC8882379
OpenAlexW4212841575

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.