Evidence map›Paper›PMID 35233439›Full record

ArticleOptica2021

Rapid chemically selective 3D imaging in the mid-infrared.

Eric O Potma, David Knez, Yong Chen, Yulia Davydova, Amanda Durkin, Alexander Fast, Mihaela Balu, Brenna Norton-Baker, Rachel W Martin, Tommaso Baldacchini and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Optica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Mid-infrared single-photon 3D imaging.Light, science & applications · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Eric O PotmaDepartment of Chemistry, University of California Irvine, California 92697, USA.ORCID 0000-0003-3916-6131
David KnezDepartment of Chemistry, University of California Irvine, California 92697, USA.
Yong ChenEpstein Department of Industrial and Systems Engineering, University of Southern California, Los Angeles, California 90089, USA.
Yulia DavydovaDepartment of Chemistry, University of California Irvine, California 92697, USA.
Amanda DurkinBeckman Laser Institute, University of California Irvine, California 92697, USA.
Alexander FastBeckman Laser Institute, University of California Irvine, California 92697, USA.ORCID 0000-0001-8963-5405
Mihaela BaluBeckman Laser Institute, University of California Irvine, California 92697, USA.
Brenna Norton-BakerDepartment of Chemistry, University of California Irvine, California 92697, USA.
Rachel W MartinDepartment of Chemistry, University of California Irvine, California 92697, USA.
Tommaso BaldacchiniDepartment of Chemistry, University of California Irvine, California 92697, USA.ORCID 0000-0001-9246-1653
Dmitry A FishmanDepartment of Chemistry, University of California Irvine, California 92697, USA.ORCID 0000-0001-6287-2128

Funding

Acquisition of nonlinear optical microscopy platform for advanced tissue imagingS10OD028698 · OD · UNIVERSITY OF CALIFORNIA-IRVINE · PI POTMA, ERIC OLAF · 2020 to 2020
$1.6M
High-resolution spectroscopic imaging with infrared nonlinear optical (IR-NLO) microscopyR01GM132506 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI POTMA, ERIC OLAF · 2019 to 2022
$742k
NIGMS NIH HHS R01 GM132506NIH HHS S10 OD028698
6 · The paper itself

Abstract

The emerging technique of mid-infrared optical coherence tomography (MIR-OCT) takes advantage of the reduced scattering of MIR light in various materials and devices, enabling tomographic imaging at deeper penetration depths. Because of challenges in MIR detection technology, the image acquisition time is, however, significantly longer than for tomographic imaging methods in the visible/near-infrared. Here we demonstrate an alternative approach to MIR tomography with high-speed imaging capabilities. Through femtosecond nondegenerate two-photon absorption of MIR light in a conventional Si-based CCD camera, we achieve wide-field, high-definition tomographic imaging with chemical selectivity of structured materials and biological samples in mere seconds.

Identifiers

PMID35233439
PMCPMC8884451

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.