Evidence map›Paper›PMID 35233370›Full record

ArticleJournal of clinical and translational hepatology2022

High Frame Rate Contrast-enhanced Ultrasound Helps Differentiate Malignant and Benign Focal Liver Lesions.

Xiang Fei, Peng Han, Bo Jiang, Lianhua Zhu, Wenshuo Tian, Maodong Sang, Xirui Zhang, Yaqiong Zhu, Yukun Luo

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical and translational hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Qualitative and quantitative analysis of solid renal tumors by high-frame-rate contrast-enhanced ultrasound.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  7. Article
  8. Compared with SonoVueQuantitative imaging in medicine and surgery · 2024
    Article
  9. Article
  10. Review
  11. Value of high frame rate contrast enhanced ultrasound in gallbladder wall thickening in non-acute setting.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiang FeiDepartment of Ultrasound, The First Medical Centre, Chinese PLA General Hospital, Beijing, China.
Peng HanDepartment of Ultrasound, The First Medical Centre, Chinese PLA General Hospital, Beijing, China.
Bo JiangDepartment of Ultrasound, The First Medical Centre, Chinese PLA General Hospital, Beijing, China.
Lianhua ZhuDepartment of Ultrasound, The First Medical Centre, Chinese PLA General Hospital, Beijing, China.
Wenshuo TianClinical Research Division of Ultrasound Imaging System, Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China.
Maodong SangR&D Division of Ultrasound Imaging System, Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China.
Xirui ZhangR&D Division of Ultrasound Imaging System, Shenzhen Mindray Bio-Medical Electronics Co., Ltd., Shenzhen, Guangdong, China.
Yaqiong ZhuDepartment of Ultrasound, The First Medical Centre, Chinese PLA General Hospital, Beijing, China.
Yukun LuoDepartment of Ultrasound, The First Medical Centre, Chinese PLA General Hospital, Beijing, China.
Chinese PLA General Hospital · CNMindray (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThis study aimed to evaluate the diagnostic performance of high frame rate contrast-enhanced ultrasound (H-CEUS) of focal liver lesions (FLLs).

methodsFrom July 2017 to June 2019, conventional contrast-enhanced ultrasound (C-CEUS) and H-CEUS were performed in 78 patients with 78 nodules. The characteristics of C-CEUS and H-CEUS in malignant and benign groups and the differences between different lesion sizes (1-3 cm, 3-5 cm, or >5 cm) of C-CEUS and H-CEUS were examined. The diagnostic performance of C-CEUS and H-CEUS was analyzed. The chi-square test or Fisher's exact test was used to assess inter-group differences. The receiver operating characteristic curve was plotted to determine the diagnostic performance of C-CEUS and H-CEUS.

resultsThere were significant differences in the enhancement area, fill-in direction and vascular architecture between C-CEUS and H-CEUS for both benign and malignant lesions (all

conclusionsH-CEUS provided more vascular information which could help differentiate malignant from benign FLLs, especially for lesions 1-3 cm in size.

Indexed as

Contrast-enhanced ultrasoundFocal liver lesionHepatocellular carcinomaHigh frame rate

Identifiers

PMID35233370
PMCPMC8845153
OpenAlexW3180280879

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.