ArticleThe Pan African medical journal2021
Prevalence and patterns of birth defects among newborns in southwestern Ethiopia: a retrospective study.
Article in The Pan African medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 8 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 8 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- A Silent Epidemic of Congenital Anomalies and Its Predictors Among Newborns in Ethiopia: A Systematic Review and Meta-Analysis.Public health reviews · 2026Pooled it
- Birth prevalence and determinants of neural tube defects among newborns in Ethiopia: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Prevalence and associated factors of congenital anomalies in Ethiopia: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Birth prevalence and risk factors of neural tube defects in Ethiopia: a systematic review and meta-analysis.BMJ open · 2023Pooled it
- Congenital anomalies and risk factors in Africa: a systematic review and meta-analysis.BMJ paediatrics open · 2023Pooled it
- Structural congenital anomalies in resource limited setting, 2023: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Birth prevalence of neural tube defects in eastern Africa: a systematic review and meta-analysis.BMC neurology · 2022Pooled it
- Magnitude and determinants of neural tube defect in Africa: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2021Pooled it
- Determinants of congenital anomalies among newborns in public hospitals of Northern Ethiopia: case-control study design.Scientific reports · 2026Article
- Prevalence of major structural congenital abnormalities detected on infant surface examination in Botswana, 2014-2022: a birth outcomes surveillance study.BMJ paediatrics open · 2026Article
- The prevalence of neural tube defects in eastern Ethiopia: A population-based surveillance.PLOS global public health · 2026Article
- Kidney transplants in Nepali migrant workers: health and employment insights.Annals of medicine and surgery (2012) · 2025Article
- Prevalence of neural tube defects among pregnant women in Addis Ababa: a community-based study using prenatal ultrasound examination.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Article
- Neural Tube Defects and Folate Deficiency: Is DNA Repair Defective?International journal of molecular sciences · 2023Review
- Prevalence and associated factors of structural congenital anomalies in resource limited setting, 2023: a systematic review and meta-analysis.Frontiers in pediatrics · 2023Review
- Burden of Neural Tube Defects and Their Associated Factors in Africa: A Systematic Review and Meta-Analysis.International journal of pediatrics · 2023Review
- Red blood cell folate level and associated factors of folate insufficiency among pregnant women attending antenatal care during their first trimester of pregnancy in Addis Ababa, Ethiopia.SAGE open medicine · 2022Article
- Magnitude and Associated Factors of Neural Tube Defects in Ethiopia: A Systematic Review and Meta-Analysis.Global pediatric health · 2020Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionprenatal development could be considered normal or abnormal. Abnormal development occurs because of interference of normal development from genetic disorders, environmental factors, and multifactorial inheritances during the critical period of embryogenesis. The present study was aimed at evaluating the prevalence and patterns of birth defects among newborns in southwestern Ethiopia.
methodsinstitutions-based cross-sectional study design was conducted in six purposively selected hospitals in southwestern Ethiopia based on their caseload. The study included data's from 2011 to 2015, during which 45,951 deliveries were recorded. All records of births in the selected hospitals were screened from medical records to identify the presence and types of birth defects.
resultsout of twenty-one different birth defects identified, nearly half of them belong to anencephaly and hydrocephalus. Five types of birth defects, namely: anencephaly (25.0%), hydrocephalus (24.6%), spina bifida (13.1%), meningomyelocele (7.1%), and umbilical hernia (4.8%) accounted for about three-fourths (75%) of all recorded birth defects. The prevalence rate of birth defects at birth was 55 per 10,000 births.
conclusionin the present study, the neural tube defects were identified to be the most prevalent. Nearly equal proportions of birth defects occurred among male and female newborns. The majority of the mothers who gave birth to newborns with birth defects were younger than 35 years. The high prevalence of birth defects revealed in this study call for the need to implement urgent prevention strategies including but not limited to the provision of sustained family planning, youth education and antenatal care services, and strict observation of rational medication use during pregnancy to curb the possible occurrences of the birth defect.
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