ArticleScientific reports2022
Oceanographic setting influences the prokaryotic community and metabolome in deep-sea sponges.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- Ammonia oxidation and recalcitrant carbon degradation fuel mixotrophic growth in the symbiont community of a deep-sea sponge.Microbiome · 2026Article
- The Chemistry and Pharmacology of the Alkaloid Barettin and Its Analogues from the Marine SpongeMarine drugs · 2026Review
- New Compounds From the Deep-sea Sponge Mycale lingua.Chemistry & biodiversity · 2026Article
- New insights into the microbiome of the deep-sea spongeMicrobial genomics · 2026Article
- The Role of Nucleotide Sequencing in Natural Product Drug Discovery.Journal of natural products · 2025Review
- Connectivity and Adaptation Patterns of the Deep-Sea Ground-Forming Sponge Geodia hentscheli Across Its Entire Distribution.Molecular biology and evolution · 2025Article
- Article
- Microbiome changes in the spongeFrontiers in microbiology · 2025Article
- Article
- Prokaryotic communities of the French Polynesian sponge Dactylospongia metachromia display a site-specific and stable diversity during an aquaculture trial.Antonie van Leeuwenhoek · 2024Article
- High compositional and functional similarity in the microbiome of deep-sea sponges.The ISME journal · 2024Article
- Article
- Putative past, present, and future spatial distributions of deep-sea coral and sponge microbiomes revealed by predictive models.ISME communications · 2024Article
- Candidatus Nemesobacterales is a sponge-specific clade of the candidate phylum Desulfobacterota adapted to a symbiotic lifestyle.The ISME journal · 2023Article
- A Study of Sponge Symbionts from Different Light Habitats.Microbial ecology · 2023Article
- Whole genome sequence of the deep-sea sponge Geodia barretti (Metazoa, Porifera, Demospongiae).G3 (Bethesda, Md.) · 2023Article
- Sponge holobionts shift their prokaryotic communities and antimicrobial activity from shallow to lower mesophotic depths.Antonie van Leeuwenhoek · 2022Article
- Bacteria Associated with Benthic Invertebrates from Extreme Marine Environments: Promising but Underexplored Sources of Biotechnologically Relevant Molecules.Marine drugs · 2022Review
- Review
- Marine Sponge Endosymbionts: Structural and Functional Specificity of the Microbiome withinMicrobiology spectrum · 2022Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marine sponges (phylum Porifera) are leading organisms for the discovery of bioactive compounds from nature. Their often rich and species-specific microbiota is hypothesised to be producing many of these compounds. Yet, environmental influences on the sponge-associated microbiota and bioactive compound production remain elusive. Here, we investigated the changes of microbiota and metabolomes in sponges along a depth range of 1232 m. Using 16S rRNA gene amplicon sequencing and untargeted metabolomics, we assessed prokaryotic and chemical diversities in three deep-sea sponge species: Geodia barretti, Stryphnus fortis, and Weberella bursa. Both prokaryotic communities and metabolome varied significantly with depth, which we hypothesized to be the effect of different water masses. Up to 35.5% of microbial ASVs (amplicon sequence variants) showed significant changes with depth while phylum-level composition of host microbiome remained unchanged. The metabolome varied with depth, with relative quantities of known bioactive compounds increasing or decreasing strongly. Other metabolites varying with depth were compatible solutes regulating osmolarity of the cells. Correlations between prokaryotic community and the bioactive compounds in G. barretti suggested members of Acidobacteria, Proteobacteria, Chloroflexi, or an unclassified prokaryote as potential producers.
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