ArticleNature communications2022
Feedforward and feedback interactions between visual cortical areas use different population activity patterns.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 93 papers.
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Who cites it
93 citing papers in PubMed.
- Network geometry shapes the transformation of task representations across the human cortex.Nature neuroscience · 2026Article
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- Assessment of Vigilance Recovery in Rats Following Anesthesia Using a Touchscreen-Based Continuous Performance Task.Anesthesiology · 2026Article
- Loss of neuronal population organization links pathology to behavior in a model of Alzheimer's disease.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- A hybrid micro-ECoG for functionally targeted multi-site and multi-scale investigation.Cell reports methods · 2026Article
- I Can't Hear You Both at the Same Time: A Temporal Dilemma During Inter-Regional Communication.eNeuro · 2026Article
- Redundant prefrontal hemispheres adapt storage strategy to working memory demands.Nature communications · 2026Article
- Noise-invariant representations of sound emerge along the canonical cortical hierarchy.PLoS biology · 2026Article
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- A communication subspace relays context-dependent actions from human prefrontal to motor cortex.Nature neuroscience · 2026Article
- Compositionality of social gaze in the prefrontal-amygdala circuits.Nature communications · 2026Article
- Independence and coherence in temporal sequence computation across the fronto-parietal network.Nature communications · 2026Article
- Brain-wide arousal signals are segregated from movement planning in the superior colliculus of the macaque.eLife · 2026Article
- Input-dependent directionality of interactions between cortical areas.bioRxiv : the preprint server for biology · 2026Article
- Decomposing the modulation of interactions between neuronal populations.bioRxiv : the preprint server for biology · 2026Article
- UltraFast Layer-Resolved Encoding (uFLARE) functional MRI deciphers bidirectional signaling from spontaneous activity.Nature communications · 2026Article
- Interactions across hemispheres in prefrontal cortex reflect global cognitive processing.Nature communications · 2026Article
- Article
- How the visual brain can learn to parse images using a multiscale, incremental grouping process.PLoS computational biology · 2026Article
33 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Brain function relies on the coordination of activity across multiple, recurrently connected brain areas. For instance, sensory information encoded in early sensory areas is relayed to, and further processed by, higher cortical areas and then fed back. However, the way in which feedforward and feedback signaling interact with one another is incompletely understood. Here we investigate this question by leveraging simultaneous neuronal population recordings in early and midlevel visual areas (V1-V2 and V1-V4). Using a dimensionality reduction approach, we find that population interactions are feedforward-dominated shortly after stimulus onset and feedback-dominated during spontaneous activity. The population activity patterns most correlated across areas were distinct during feedforward- and feedback-dominated periods. These results suggest that feedforward and feedback signaling rely on separate "channels", which allows feedback signals to not directly affect activity that is fed forward.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.