Evidence map›Paper›PMID 35232487›Full record

ArticleJournal of pharmaceutical policy and practice2022

A multi-criteria decision analysis (MCDA) tool for purchasing off-patent oncology medicines in Egypt.

Baher Elezbawy, Ahmad Nader Fasseeh, Amal Sedrak, Randa Eldessouki, Mary Gamal, Mariam Eldebeiky, Hanaa Amer, Shimaa Akeel, Ahmad Morsy, Amira Amin and 3 more

Abstract read
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Article in Journal of pharmaceutical policy and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Baher ElezbawySyreon Middle East, Alexandria, Egypt. baher.elezbawy@gmail.com.ORCID http://orcid.org/0000-0003-1335-9285
Ahmad Nader FasseehSyreon Middle East, Alexandria, Egypt.
Amal SedrakThe Egyptian Authority for Unified Procurement, Medical Supply, and The Management of Medical Technology (UPA), Cairo, Egypt.
Randa EldessoukiFayoum University, Fayoum, Egypt.
Mary GamalThe Egyptian Authority for Unified Procurement, Medical Supply, and The Management of Medical Technology (UPA), Cairo, Egypt.
Mariam EldebeikyThe Egyptian Authority for Unified Procurement, Medical Supply, and The Management of Medical Technology (UPA), Cairo, Egypt.
Hanaa AmerAin Shams University, Cairo, Egypt.
Shimaa AkeelThe Egyptian Authority for Unified Procurement, Medical Supply, and The Management of Medical Technology (UPA), Cairo, Egypt.
Ahmad MorsyPresidential Program for Women's Health, Ministry of Health and Population (MoHP, Cairo, Egypt.
Amira AminEgyptian Pharmaceutical Vigilance Center, Egyptian Drug Authority (EDA), Cairo, Egypt.
Amr ShafikAin Shams University, Cairo, Egypt.
Sherif AbazaSyreon Middle East, Cairo, Egypt.
Zoltán KalóSemmelweis University, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMulti- criteria decision analysis (MCDA) can assist policymakers in objectively choosing between alternative therapeutic options based on multiple value attributes. Our aim was to create an MCDA tool for the national tenders of off-patent oncology medicines in Egypt.

methodsAn initial list of criteria was developed through a literature review complemented by local expert interviews. Price or cost-related criteria were excluded to abide by the national regulations of the tender process. Next, a workshop hosting diversified stakeholders representing different governmental bodies was held. Anonymous voting was used to rank and weigh the criteria as well as assigning scores. Price was added as a separate step to identify best option based on price per point. The tool was then tested on a national tender sample of off-patent oncology medicines to assess its performance, and it was readjusted accordingly in a second workshop.

resultsSeven non-price criteria were selected, including use in reference countries (23.49% weight), equivalence with the reference product (18.79%), manufacturing quality (15.53%), provision of pharmacovigilance services (12.94%), supply reliability (10.78%), previous use in local settings (9.8%) and macroeconomic benefit (8.67%). A medicine receives a score ranging from 0 to 100% of each criterion's weight. The aggregated score is calculated on a hundred-point scale. Based on participants' consensus, an overall score of 65 was set as a cut-off for passing the technical eligibility phase of the tendering process. Any product receiving a lower score would be disqualified from the tender. For qualified products, the lower price per point represents preferential option for the national tender.

conclusionsThe created MCDA tool is capable of objectively comparing similar off-patent oncology medicines by considering multiple value attributes and providing reliable scoring functions for each.

Indexed as

MCDAMulti- criteria decision analysisOff-patent pharmaceuticalsOncology medicinesPurchasingTendering process

Identifiers

PMID35232487
PMCPMC8886839

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.