Evidence map›Paper›PMID 35232472›Full record

ReviewJournal of animal science and biotechnology2022

A review of the amino acid metabolism in placental function response to fetal loss and low birth weight in pigs.

Chengquan Tan, Zihao Huang, Wenyu Xiong, Hongxuan Ye, Jinping Deng, Yulong Yin

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of animal science and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chengquan Tan *Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Zihao Huang *Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Wenyu XiongGuangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Hongxuan YeGuangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, 510642, Guangdong, China.
Jinping DengGuangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, 510642, Guangdong, China. dengjinping@scau.edu.cn.ORCID http://orcid.org/0000-0001-9290-1807
Yulong YinNational Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, Hunan, China. yinyulong@isa.ac.cn.
South China Agricultural University · CNChinese Academy of Sciences · CN

Funding

National Key R&D Program of China 2021YFD1300401National Natural Science Foundation of China 31902165Natural Science Foundation of Guangdong Province 2021A1515012116
6 · The paper itself

Abstract

The fertility of sows mainly depends on the embryo losses during gestation and the survival rate of the post-farrowing piglets. The selection of highly-prolific sows has been mainly focused on the selection of genotypes with high ovulatory quota. However, in the early- and post-implantation stages, the rate of embryo losses was increased with the increase of zygotes. Among the various factors, placental growth and development is the vital determinant for fetal survival, growth, and development. Despite the potential survival of fetuses with deficient placental development, their life-conditions and growth can be damaged by a process termed intrauterine growth retardation (IUGR). The newborn piglets affected by IUGR are prone to increased morbidity and mortality rates; meanwhile, the growth, health and welfare of the surviving piglets will remain hampered by these conditions, with a tendency to exacerbate with age. Functional amino acids such as glycine, proline, and arginine continue to increase with the development of placenta, which are not only essential to placental growth (including vascular growth) and development, but can also be used as substrates for the production of glutathione, polyamines and nitric oxide to benefit placental function in many ways. However, the exact regulation mechanism of these amino acids in placental function has not yet been clarified. In this review, we provide evidence from literature and our own work for the role and mechanism of dietary functional amino acids during pregnancy in regulating the placental functional response to fetal loss and birth weight of piglets. This review will provide novel insights into the response of nutritionally nonessential amino acids (glycine and proline) to placental development as well as feasible strategies to enhance the fertility of sows.

Indexed as

Amino acidsBirth weightFetal lossPigsPlacenta

Identifiers

PMID35232472
PMCPMC8889744
OpenAlexW4214929226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.