Evidence map›Paper›PMID 35232404›Full record

SynthesisBMC psychiatry2022

A meta-analysis on neural changes of cognitive training for mental disorders in executive function tasks: increase or decrease brain activation?

Jin Yang Li, Huiqin Wu, Shiting Yuan, Chun Wang, Qian Wang, Yuan Zhong, Ning Zhang, Kathi Heffner, Peter T Fox

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in BMC psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jin Yang LiNan jing Brain Hospital affiliated to Nanjing Medical University, Nanjing, 210029, Jiangsu, China.
Huiqin WuNan jing Brain Hospital affiliated to Nanjing Medical University, Nanjing, 210029, Jiangsu, China.
Shiting YuanNan jing Brain Hospital affiliated to Nanjing Medical University, Nanjing, 210029, Jiangsu, China.
Chun WangNan jing Brain Hospital affiliated to Nanjing Medical University, Nanjing, 210029, Jiangsu, China. chun_wang@njmu.edu.cn.
Qian WangBeiJing TianTan Hospital, Capital Medical University, Beijing, 100050, China.
Yuan ZhongSchool of Psychology, Nanjing Normal University, Nanjing, 210029, Jiangsu, China.
Ning ZhangNan jing Brain Hospital affiliated to Nanjing Medical University, Nanjing, 210029, Jiangsu, China.
Kathi HeffnerDepartment of Psychiatry, University of Rochester School of Nursing, Rochester, New York, 14622, USA.
Peter T FoxNan jing Brain Hospital affiliated to Nanjing Medical University, Nanjing, 210029, Jiangsu, China.
Nanjing Medical University · CNNanjing Brain Hospital · CNBeijing Tian Tan Hospital · CNNanjing Normal University · CNUniversity of Rochester · US

Funding

Meta-anaylsis in human brain mappingR01MH074457 · NIMH · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI FOX, PETER THORNTON · 2006 to 2024
$10.5M
NIMH NIH HHS R01 MH074457
6 · The paper itself

Abstract

backgroundCognitive impairment is often found in patients with psychiatric disorders, and cognitive training (CT) has been shown to help these patients. To better understand the mechanisms of CT, many neuroimaging studies have investigated the neural changes associated with it. However, the results of those studies have been inconsistent, making it difficult to draw conclusions from the literature. Therefore, the objective of this meta-analysis was to identify consistent patterns in the literature of neural changes associated with CT for psychiatric disorders.

methodsWe searched for cognitive training imaging studies in PubMed, Cochrane library, Scopus, and ProQuest electronic databases. We conducted an activation likelihood estimation (ALE) for coordinate-based meta-analysis of neuroimaging studies, conduct behavioral analysis of brain regions identified by ALE analysis, conduct behavioral analysis of brain regions identified by ALE analysis, and then created a functional meta-analytic connectivity model (fMACM) of the resulting regions.

resultsResults showed that CT studies consistently reported increased activation in the left inferior frontal gyrus (IFG) and decreased activation in the left precuneus and cuneus from pre- to post- CT.

conclusionCT improves cognitive function by supporting language and memory function, and reducing neuronal resources associated with basic visual processing.

Indexed as

Cognition DisordersExecutive FunctionBrainBrain MappingCognitionHumansMagnetic Resonance ImagingCognitive trainingMental disorderMeta-analysisNeuroimaging

Identifiers

PMID35232404
PMCPMC8886766
OpenAlexW4214688846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.