ArticleAudiology & neuro-otology2022
Efficacy of Oral Steroids for Acute Acoustic Trauma.
Article in Audiology & neuro-otology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Ototoxicity of a Single Fulminant Episode of Acute Otitis Media in Children: A Long-Term Follow-Up.Audiology research · 2026Article
- Beyond standard audiometry: Auditory dysfunction and steroid treatment outcomes in young adults following acoustic trauma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Evaluating the Sequelae of Mastoidectomy for Acute Mastoiditis: A Long-Term Follow-Up Study of Mastoid Function.Journal of clinical medicine · 2025Article
- Pan-caspase inhibitor protects against noise-induced hearing loss in a rodent model.Frontiers in neuroscience · 2025Article
- Perforated Concave Earplug (pCEP): A Proof-of-Concept Earplug to Improve Sound Localization without Compromising Noise Attenuation.Sensors (Basel, Switzerland) · 2023Article
- Noise-Induced Hearing Loss.Journal of clinical medicine · 2023Review
- Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to study the effect of steroid treatment on new-onset sensorineural hearing loss (SNHL) in subjects presenting shortly after an audiometry-confirmed acute acoustic trauma (AAT) injury. STUDY
designThis is a case-control study.
methodsWe identified healthy military personnel who presented with AAT injury to the Israeli Defense Forces Medical Corps Otolaryngology/Audiology Services during 2016-2020. Patients were nonrandomly allocated to a treatment arm, where they received steroids (prednisone, 1 mg/kg, 60 mg maximal daily dose), administered for either ≥7 days or <7 days, or to a control arm, in which no treatment was offered besides loud noise avoidance. Audiometries were conducted within 7 days following the AAT and within 1 month later. We compared changes in bone conduction (BC) and air conduction (AC) thresholds at 2-8 kHz.
resultsOf the 263 enrolled subjects, 137 (52%) received steroids and 126 (48%) received no treatment. Subjects who were treated early (<24 h) with high-dose steroids and for ≥7 days demonstrated significantly better hearing outcomes, compared with the nontreatment group. Subjects in the steroids group demonstrated 13-14 dB average improvement in BC thresholds at 3 and 4 kHz (p = 0.001) and additional 7-8 dB average improvement in AC thresholds at 6 and 8 kHz, compared with the nontreatment group (p < 0.0001). These observations were more compelling in patients who initially presented with worse hearing losses (>35 dB). No statistically significant differences were observed in AC/BC pure tone average between the two groups.
conclusionsEarly oral steroids are recommended in AAT injuries and were shown to improve hearing outcomes within 1 month.
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Registered trials
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