Evidence map›Paper›PMID 35231846›Full record

ArticleNeurobiology of aging2022

Cognitively stimulating environments and cognitive reserve: the case of personal social networks.

Siyun Peng, Adam R Roth, Liana G Apostolova, Andrew J Saykin, Brea L Perry

Abstract read
In one paragraph

Article in Neurobiology of aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. The social environment and cognitive aging over the life course: laying out critical concepts and research gaps.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Sensory Health Among Older Adults in the United States: A Neighborhood Context Approach.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Bridging Social Capital Potential and Alzheimer's Disease Mortality Rates.Socius : sociological research for a dynamic world
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Siyun PengDepartment of Sociology & Network Science Institute, Indiana University, Bloomington, IN, USA. Electronic address: siypeng@iu.edu.
Adam R RothDepartment of Sociology & Network Science Institute, Indiana University, Bloomington, IN, USA.
Liana G ApostolovaDepartment of Neurology, Indiana University, Indianapolis, IN, USA.
Andrew J SaykinDepartment of Radiology and Imaging Sciences & Indiana Alzheimer Disease Center, Indiana University, Indianapolis, IN, USA.
Brea L PerryDepartment of Sociology & Network Science Institute, Indiana University, Bloomington, IN, USA.

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI FOROUD, TATIANA M. · 1991 to 2020
$37.3M
Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Research Education ComponentP30AG072976 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI ANDREW J SAYKIN · 2021 to 2026
$24.1M
Understanding how social connectedness protects older adults' cognitive health: the role of social cognitionR01AG070931 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI KRENDL, ANNE CATHERINE, PERRY, BREA LOUISE · 2020 to 2024
$3.6M
Leveraging Neuroimaging Biomarkers to Understand the Role of Social Networks in Alzheimer's DiseaseR01AG057739 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI APOSTOLOVA, LIANA G, PERRY, BREA LOUISE · 2018 to 2022
$3.5M
Social Networks in Alzheimer Disease 2.0.R37AG057739 · NIA · TRUSTEES OF INDIANA UNIVERSITY · PI PERRY, BREA LOUISE · 2024 to 2025
$1.5M
NCATS NIH HHS UL1 TR002529NIA NIH HHS P30 AG010133NIA NIH HHS P30 AG072976NIA NIH HHS R01 AG057739NIA NIH HHS R01 AG070931NIA NIH HHS R37 AG057739
6 · The paper itself

Abstract

Cognitively stimulating environments are thought to be protective of cognitive decline and onset of Alzheimer's disease and related dementias (ADRD) through the development of cognitive reserve (CR). CR refers to cognitive adaptability that buffers the impact of brain pathology on cognitive function. Despite the critical need to identify cognitively stimulating environments to build CR, there is no consensus regarding which environmental determinants are most effective. Rather, most studies use education as proxies for CR and little is known about the association between older adults' personal social networks and CR. Using neuroimaging data from 135 older adults participating in the Social Networks in Alzheimer Disease (SNAD) study, this article adopted a residual method for measuring CR and found that large network size, high network diversity, and loosely connected networks were positively associated with greater CR. These results suggest that expansive social networks in later life may constitute cognitively stimulating environments which can be leveraged to build CR and reduce the burden of ADRD.

Indexed as

Alzheimer DiseaseCognitive DysfunctionCognitive ReserveAgedCognitionHumansSocial NetworkingAlzheimer's diseaseCognitively stimulating environmentsCognitive reserveSocial networks

Identifiers

PMID35231846
PMCPMC9019994

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.