ArticleNeuroImage2022
Directed coupling in multi-brain networks underlies generalized synchrony during social exchange.
Article in NeuroImage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Together we sync: a systematic qualitative and quantitative review of fMRI hyperscanning studies.Social cognitive and affective neuroscience · 2026Pooled it
- Social interactions between people of same and different generations shape longitudinal changes in interpersonal neural synchrony, loneliness, and social connection.PLoS biology · 2026Article
- Understanding and explaining differences across minds in social interaction: insights from social neuroscience and clinical psychiatry.European archives of psychiatry and clinical neuroscience · 2025Article
- Eigenmodes of the deep unconscious: the neuropsychology of Jungian archetypes and psychedelic experience.Neuroscience of consciousness · 2025Review
- Synchrony Across Brains.Annual review of psychology · 2025Review
- Stage 1 registered report examining agency and outcome valence on inter-brain synchrony during dyadic moral judgments.Frontiers in psychology · 2025Article
- Inter-brain synchrony to delineate the social impairment in autism spectrum disorder: a systematic review on hyperscanning studies.Psychoradiology · 2025Review
- Article
- Active Inference and Social Actors: Towards a Neuro-Bio-Social Theory of Brains and Bodies in Their Worlds.Kolner Zeitschrift fur Soziologie und Sozialpsychologie · 2024Article
- Arbitrary methodological decisions skew inter-brain synchronization estimates in hyperscanning-EEG studies.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Disorganized Communication and Social Dysfunction in Schizophrenia: Emerging Concepts and Methods.Current psychiatry reports · 2023Review
- [Working in a team and mental health].Der Nervenarzt · 2023Review
- Therapeutic touch and therapeutic alliance in pediatric care and neonatology: An active inference framework.Frontiers in pediatrics · 2023Article
- Hyperscanning fNIRS data analysis using multiregression dynamic models: an illustration in a violin duo.Frontiers in computational neuroscience · 2023Article
- Interacting brains revisited: A cross-brain network neuroscience perspective.Human brain mapping · 2022Article
- The Role of Neurobiological Bases of Dyadic Emotion Regulation in the Development of Psychopathology: Cross-Brain Associations Between Parents and Children.Clinical child and family psychology review · 2022Review
- Markov blankets in the brain.Neuroscience and biobehavioral reviews · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Advances in social neuroscience have made neural signatures of social exchange measurable simultaneously across people. This has identified brain regions differentially active during social interaction between human dyads, but the underlying systems-level mechanisms are incompletely understood. This paper introduces dynamic causal modeling and Bayesian model comparison to assess the causal and directed connectivity between two brains in the context of hyperscanning (h-DCM). In this setting, correlated neuronal responses become the data features that have to be explained by models with and without between-brain (effective) connections. Connections between brains can be understood in the context of generalized synchrony, which explains how dynamical systems become synchronized when they are coupled to each another. Under generalized synchrony, each brain state can be predicted by the other brain or a mixture of both. Our results show that effective connectivity between brains is not a feature within dyads per se but emerges selectively during social exchange. We demonstrate a causal impact of the sender's brain activity on the receiver of information, which explains previous reports of two-brain synchrony. We discuss the implications of this work; in particular, how characterizing generalized synchrony enables the discovery of between-brain connections in any social contact, and the advantage of h-DCM in studying brain function on the subject level, dyadic level, and group level within a directed model of (between) brain function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.