Evidence map›Paper›PMID 35231604›Full record

ArticleMolecular therapy : the journal of the American Society of Gene Therapy2022

Env-independent protection of intrarectal SIV challenge by vaccine induction of Gag/Vif-specific CD8

Hiroshi Ishii, Kazutaka Terahara, Takushi Nomura, Midori Okazaki, Hiroyuki Yamamoto, Tsugumine Shu, Hiromi Sakawaki, Tomoyuki Miura, David I Watkins, Tetsuro Matano

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy : the journal of the American Society of Gene Therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. HIV T-cell immunogen design and delivery.Current opinion in HIV and AIDS · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Hiroshi IshiiAIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
Kazutaka TeraharaResearch Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo 162-8640, Japan.
Takushi NomuraAIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
Midori OkazakiAIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
Hiroyuki YamamotoAIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
Tsugumine ShuID Pharma Co., Ltd., Ibaraki 300-2611, Japan.
Hiromi SakawakiInstitute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
Tomoyuki MiuraInstitute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.
David I WatkinsDepartment of Pathology, George Washington Medical School, Washington, DC 20052, USA.
Tetsuro MatanoAIDS Research Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan; Institute of Medical Science, University of Tokyo, Tokyo 108-8639, Japan; Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto 860-0811, Japan. Electronic address: tmatano@nih.go.jp.
National Institute of Infectious Diseases · JPKyoto University · JPID Pharma (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective T cell induction is an important strategy in HIV-vaccine development. However, it has been indicated that vaccine-induced HIV-specific CD4

Indexed as

AIDS VaccinesHIV InfectionsSAIDS VaccinesSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAnimalsCD8-Positive T-LymphocytesMacaca mulattaAIDS VaccinesSAIDS VaccinesCD4(+) T cellsCD8(+) T cellsHIVimmunogen designSIVvaccine

Identifiers

PMID35231604
PMCPMC9092394
OpenAlexW4214703079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.