Evidence map›Paper›PMID 35231045›Full record

ArticlePloS one2022

Lateralization of bladder function in normal female canines.

Dania Giaddui, Danielle S Porreca, Ekta Tiwari, Nagat A Frara, Lucas J Hobson, Mary F Barbe, Alan S Braverman, Justin M Brown, Michel A Pontari, Michael R Ruggieri

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Dania GiadduiDepartment of Cardiovascular Sciences and Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Danielle S PorrecaDepartment of Cardiovascular Sciences and Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Ekta TiwariDepartment of Cardiovascular Sciences and Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Nagat A FraraDepartment of Cardiovascular Sciences and Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Lucas J HobsonDepartment of Cardiovascular Sciences and Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Mary F BarbeDepartment of Cardiovascular Sciences and Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.ORCID 0000-0002-5235-9803
Alan S BravermanDepartment of Cardiovascular Sciences and Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Justin M BrownDepartment of Neurosurgery, Neurosurgery Paralysis Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America.
Michel A PontariDepartment of Urology, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Michael R RuggieriDepartment of Cardiovascular Sciences and Center for Translational Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, United States of America.
Temple University · USMassachusetts General Hospital · USShriners Hospitals for Children - Philadelphia · US

Funding

Bladder, Urethra and Anal Sphincter ReinnervationR01NS070267 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI BARBE, MARY F · 2010 to 2024
$8.2M
NINDS NIH HHS R01 NS070267
6 · The paper itself

Abstract

This study aimed to identify potential lateralization of bladder function. Electrical stimulation of spinal roots or the pelvic nerve's anterior vesical branch was performed bilaterally in female dogs. The percent difference between the left and right stimulation-induced increased detrusor pressure was determined. Bladders were considered left or right-sided if differences were greater or less than 25% or 10%. Based on differences of 25%, upon stimulation of spinal roots, bladders were left-sided in 17/44 (38.6%), right-sided in 12/44 (27.2%) and bilateral in 15/44 (34.2%). Using ± 10%, 48% had left side dominance (n = 21/44), 39% had right side dominance (n = 17/44), and 14% were bilateral (n = 6/44). With stimulation of the pelvic nerve's anterior vesical branch in 19 dogs, bladders were left-sided in 8 (42.1%), right-sided in 6 (31.6%) and bilateral in 5 (26.3%) using 25% differences and left side dominance in 8 (43%), right sided in 7 (37%) and bilateral in 4 (21%) using 10% differences. These data suggest lateralization of innervation of the female dog bladder with left- and right-sided lateralization occurring at similar rates. Lateralization often varied at different spinal cord levels within the same animal.

Indexed as

Urinary Tract Physiological PhenomenaAnimalsDogsElectric StimulationFemaleSpinal Nerve RootsSpinal NervesUrinary Bladder

Identifiers

PMID35231045
PMCPMC8887770
OpenAlexW4221024017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.