Evidence map›Paper›PMID 35230927›Full record

ArticlePaediatrics and international child health2021

Relationship between distance of referring facilities and haemoglobin change in children in Malawi.

Elizabeth M Keating, Jeff A Robison, Msandeni Chiume, Marissa Taddie, James A VanDerslice, L Scott Benson, Elizabeth Fitzgerald, Heather L Crouse, Michelle D Eckerle, Emily J Ciccone and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Paediatrics and international child health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06075108 (P-KIDs CARE), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06075108 narecruitingnot on this mapstarted 2024, after this paper: background citation

P-KIDs CARE: An Intervention to Address Health Systems Delays to Care for Injured Children in Tanzania

TypeinterventionalSponsorUniversity of UtahRan2024 to 2028Enrolled284ConditionsAccidental Injuries, Global Child Health, Pediatric Emergency Medicine, Public Health System ResearchArmsP-KIDs CARE
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Elizabeth M KeatingDivision of Pediatric Emergency Medicine, Department of Pediatrics, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0002-5263-6612
Jeff A RobisonDivision of Pediatric Emergency Medicine, Department of Pediatrics, University of Utah, Salt Lake City, UT, USA.
Msandeni ChiumeDepartment of Paediatrics, Kamuzu Central Hospital, Lilongwe, Malawi.
Marissa TaddieDivision of Public Health, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA.
James A VanDersliceDivision of Public Health, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA.
L Scott BensonDivision of Public Health, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA.
Elizabeth FitzgeraldDivision of Pediatric Emergency Medicine, Department of Pediatrics, University of North Carolina, Chapel Hill, NC, USA.
Heather L CrouseSection of Pediatric Emergency Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, Tx, USA.
Michelle D EckerleDivision of Pediatric Emergency Medicine, Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH, USA.ORCID 0000-0002-7716-288X
Emily J CicconeDivision of Infectious Diseases, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Christina A PorucznikDivision of Public Health, Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA.

Funding

North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR002538
6 · The paper itself

Abstract

backgroundAnaemia is a significant cause of mortality in children in sub-Saharan Africa where blood transfusion is often available only at referral hospitals. Understanding the pattern of referrals by health facilities is essential to identify the delays that affect child survival.

aimTo determine if there was a correlation between change in haemoglobin (Hb) level and distance from referring facilities to Kamuzu Central Hospital (KCH) in Malawi, and whether distance affected mortality rates.

methodsThis was a retrospective cohort study of 2259 children referred to KCH whose Hb was measured at the referring facility or at KCH. Maps were created using ArcGIS® software. The relationship between distance from KCH and change in Hb was assessed by χ

resultsThe majority of children were referred by health facilities in the Lilongwe District. When categorised as Hb <4, 4-6 or >6 g/dL, 87.0% of children remained in the same category during transfer. There was no significant relationship between Hb drop and distance from KCH. Distance from KCH was not a significant predictor of Hb level at KCH or Hb change. However, mortality rates were significantly higher in facilities that were 10-50 km from KCH than in those which were <10 km away.

conclusionsUsing distance as a proxy for time, this suggests that referring facilities are transferring children sufficiently quickly to avert significant reductions in Hb. Despite this, there is a need to identify the factors that influence the decision to transfer anaemic children.

Indexed as

AnemiaHemoglobinsBlood TransfusionChildHumansMalawiRetrospective StudiesHemoglobinsAnaemiainternational healthpublic healthsub-Saharan Africa

Identifiers

PMID35230927
PMCPMC9050928

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.