Evidence map›Paper›PMID 35230892›Full record

ArticleGut microbes

Upregulation of antimicrobial peptide expression in slc26a3-/- mice with colonic dysbiosis and barrier defect.

Archana Kini, Bei Zhao, Marijana Basic, Urmi Roy, Aida Iljazovic, Ivan Odak, Zhenghao Ye, Brigitte Riederer, Gabriella Di Stefano, Dorothee Römermann and 4 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Bicarbonate secretion and acid/base sensing by the intestine.Pflugers Archiv : European journal of physiology · 2024
    Review
  8. Article
  9. SLC26 Anion Transporters.Handbook of experimental pharmacology · 2024
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Archana KiniDepartment of Gastroenterology.
Bei ZhaoMicrobial Immune Regulation Research Group, Helmholtz Center for Infection Research, Braunschweig, Germany.
Marijana BasicInstitute of Laboratory Animal Science.
Urmi RoyMicrobial Immune Regulation Research Group, Helmholtz Center for Infection Research, Braunschweig, Germany.
Aida IljazovicMicrobial Immune Regulation Research Group, Helmholtz Center for Infection Research, Braunschweig, Germany.
Ivan OdakInstitute of Immunology Hannover Medical School Hannover, Germany.
Zhenghao YeDepartment of Gastroenterology.
Brigitte RiedererDepartment of Gastroenterology.
Gabriella Di StefanoDepartment of Gastroenterology.
Dorothee RömermannDepartment of Gastroenterology.
Christian KoeneckeInstitute of Immunology Hannover Medical School Hannover, Germany.
André BleichInstitute of Laboratory Animal Science.
Till StrowigMicrobial Immune Regulation Research Group, Helmholtz Center for Infection Research, Braunschweig, Germany.
Ursula SeidlerDepartment of Gastroenterology.
Helmholtz Centre for Infection Research · DEInstitute of Laboratory Animal Science · CNMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic defects in SLC26A3 (DRA), an intestinal Cl

Indexed as

DysbiosisGastrointestinal MicrobiomeAnimalsAntimicrobial PeptidesAntiportersColonIntestinal MucosaMiceRNA, Ribosomal, 16SSulfate TransportersUp-RegulationAntimicrobial PeptidesAntiportersRNA, Ribosomal, 16SSlc26a3 protein, mouseSulfate TransportersAnion exchangeantimicrobial peptidesgut dysbiosisinflammatory bowel diseaseintestinal electrolyte transport

Identifiers

PMID35230892
PMCPMC8890434
OpenAlexW4214502938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.