Evidence map›Paper›PMID 35230845›Full record

ArticleJournal of the American Chemical Society2022

Asymmetric Azidation under Hydrogen Bonding Phase-Transfer Catalysis: A Combined Experimental and Computational Study.

Jimmy Wang, Matthew A Horwitz, Alexander B Dürr, Francesco Ibba, Gabriele Pupo, Yuan Gao, Paolo Ricci, Kirsten E Christensen, Tejas P Pathak, Timothy D W Claridge and 3 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Asymmetric phase-transfer catalysis.Nature reviews. Chemistry · 2024
    Review
  4. Origins of High-Activity Cage-Catalyzed Michael Addition.Journal of the American Chemical Society · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Diarylureas: New Promising Small Molecules againstAntibiotics (Basel, Switzerland) · 2023
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jimmy WangChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.ORCID 0000-0002-4277-5248
Matthew A HorwitzChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Alexander B DürrChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Francesco IbbaChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.ORCID 0000-0002-2739-4156
Gabriele PupoChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.ORCID 0000-0003-3084-3888
Yuan GaoSchool of Chemistry, University of Edinburgh, Edinburgh EH9 3FJ, U.K.
Paolo RicciChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Kirsten E ChristensenChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Tejas P PathakNovartis Institutes for Biomedical Research, 22 Windsor Street, Cambridge, Massachusetts 02139, United States.ORCID 0000-0003-3858-8770
Timothy D W ClaridgeChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.ORCID 0000-0001-5583-6460
Guy C Lloyd-JonesSchool of Chemistry, University of Edinburgh, Edinburgh EH9 3FJ, U.K.ORCID 0000-0003-2128-6864
Robert S PatonDepartment of Chemistry, Colorado State University, Fort Collins, Colorado 80528, United States.ORCID 0000-0002-0104-4166
Véronique GouverneurChemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.ORCID 0000-0001-8638-5308

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asymmetric catalytic azidation has increased in importance to access enantioenriched nitrogen containing molecules, but methods that employ inexpensive sodium azide remain scarce. This encouraged us to undertake a detailed study on the application of hydrogen bonding phase-transfer catalysis (HB-PTC) to enantioselective azidation with sodium azide. So far, this phase-transfer manifold has been applied exclusively to insoluble metal alkali fluorides for carbon-fluorine bond formation. Herein, we disclose the asymmetric ring opening of

Indexed as

AzidesFluoridesAlkaliesAnionsCatalysisHydrogenHydrogen BondingKineticsSodium AzideAlkaliesAnionsAzidesFluoridesHydrogenSodium Azide

Identifiers

PMID35230845
PMCPMC8931729

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.