Evidence map›Paper›PMID 35230586›Full record

ArticleEsophagus : official journal of the Japan Esophageal Society2022

Relationship between esophageal achalasia subtypes and esophageal clearance.

Kazuto Tsuboi, Fumiaki Yano, Nobuo Omura, Masato Hoshino, Se-Ryung Yamamoto, Shunsuke Akimoto, Takahiro Masuda, Yuki Sakashita, Naoko Fukushima, Hideyuki Kashiwagi and 1 more

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Article in Esophagus : official journal of the Japan Esophageal Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

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0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Kazuto TsuboiDepartment of Surgery, Fuji City General Hospital, 50, Takashima-cho, Fuji, Shizuoka, 417-8567, Japan. kazuto@jikei.ac.jp.ORCID 0000-0002-8126-431X
Fumiaki YanoDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Nobuo OmuraDepartment of Surgery, Nishisaitama-Chuo National Hospital, Saitama, Japan.
Masato HoshinoDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Se-Ryung YamamotoDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Shunsuke AkimotoDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Takahiro MasudaDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Yuki SakashitaDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Naoko FukushimaDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.
Hideyuki KashiwagiDepartment of Surgery, Fuji City General Hospital, 50, Takashima-cho, Fuji, Shizuoka, 417-8567, Japan.
Ken EtoDepartment of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis and pathological evaluation of esophageal achalasia have been improved dramatically by the development of high-resolution manometry. It is currently known to be divided into three subtypes. However, the differences between subtypes in terms of esophageal clearance remain unclear.

aimsTo compare the pathology of subtypes in patients with esophageal achalasia from the perspective of esophageal clearance.

methodsWe classified the patients diagnosed with esophageal achalasia into three subtypes based on the high-resolution manometry findings and compared the patient background, esophagography findings, esophageal manometry findings, timed barium esophagogram (TBE) findings, and their symptoms. We also calculated the esophageal clearance rate from TBE to investigate the relationship with the subtypes.

resultsThere were 71 cases of Type I, 140 cases of Type II, and 10 cases of Type III. No differences by subtype were found in patient background or symptoms. Regarding the esophageal manometry findings, the integrated relaxation pressure was high in Type II (p = 0.0006). The esophagography revealed a mild degree of esophageal flexion in Type III (p = 0.0022) and a high degree of esophageal dilation in Type I and II (p = 0.0227). The esophageal clearance rate in descending order was: Type III, II, and I (height: p = 0.0302, width: p = 0.0008).

conclusionsThe subtypes by high-resolution manometry diagnosis had an association with the esophagography findings and best reflected the esophageal clearance, with no correlation to the patient backgrounds and symptoms.

Indexed as

Esophageal AchalasiaBarium SulfateDilatationHumansManometryBarium SulfateAchalasia subtypeEsophageal achalasiaEsophageal clearanceHigh-resolution manometryTimed barium esophagogram

Identifiers

PMID35230586

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.