ArticleThe international journal of cardiovascular imaging2022
Right ventricle systolic function and right ventricle-pulmonary artery coupling in patients with severe aortic stenosis and the early impact of TAVI.
Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Right ventricular function assessment following transcatheter aortic valve implantation/replacement (TAVI/TAVR): a systematic review and meta-analysis comparing speckle tracking and conventional echocardiographic approaches.Journal of echocardiography · 2026Pooled it
- Postoperative Right Ventriculo-Pulmonary Artery Coupling Assessed by TAPSE/PASP as a Predictor of Long-Term Outcomes After TAVI.Anatolian journal of cardiology · 2026Article
- Right ventricular to pulmonary artery uncoupling is an early predictor of poor outcome in wild-type transthyretin amyloid cardiomyopathy.The international journal of cardiovascular imaging · 2025Article
- Multiparametric Outcome Assessment After Transcatheter Aortic Valve Implantation-A Systematic Review.Journal of clinical medicine · 2025Review
- Right ventricular to pulmonary artery coupling in patients with different types of aortic stenosis undergoing TAVI.Clinical research in cardiology : official journal of the German Cardiac Society · 2025Article
- Impact of Right Heart Failure on Outcomes of Transcatheter Aortic Valve Implantation: Insights from the National Inpatient Sample.Journal of clinical medicine · 2025Article
- Impact of right ventricle-pulmonary artery coupling in patients undergoing transcatheter aortic valve implantation.The international journal of cardiovascular imaging · 2024Article
- Right Ventricle-Pulmonary Artery Coupling in Patients Undergoing Cardiac Interventions.Current cardiology reports · 2024Review
- Clinical impact of the right ventricular impairment in patients following transcatheter aortic valve replacement.Scientific reports · 2024Article
- Impact of right ventricular-pulmonary arterial coupling on clinical outcomes of tricuspid regurgitation.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022Article
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Few data are available on the prevalence of right ventricle (RV) systolic dysfunction, assessed including RV strain, and RV to pulmonary artery (PA) coupling in patients with aortic stenosis (AS) submitted to TAVI and the early effect of the procedure. We performed standard and speckle tracking echocardiography in 80 patients with severe AS the day before TAVI and within 48 h after TAVI. In all patients we measured TAPSE/PASP (cut-off for RV-PA uncoupling 0.31) and in 60/80 we were able to analyze RV global longitudinal strain (RV-GLS) and RV free wall strain (RV-FWS). RVFAC and TAPSE were impaired in 8.3% while RV-GLS and RV-FWS in 45% and 33.3% respectively before TAVI. TAPSE/PASP < 0.31 was documented in 7/80 patients (8.7%) before TAVI. These subjects differed from patients with TAPSE/PASP ≥ 0.31 for: enlarged left ventricular (LV) end-diastolic and end-systolic volumes (p < 0.001), worst LV ejection fraction (p < 0.001) and RVFAC (p < 0.001), worst RV-GLS and RV-FWS (p = 0.01 and p = 0.03) and bigger right atrium (RA) area (p < 0.001). After TAVI, RV systolic function did not improve while PASP significantly decreased (p = 0.005) driving the improvement of TAPSE/PASP (p = 0.01). Patients with TAPSE/PASP improvement (51%) differed from the others for worst pre-TAVI diastolic function (E/e' p = 0.045), RVFAC (p = 0.042), RV-GLS (p = 0.049) and RA area (p = 0.02). RV-GLS unveils RV systolic dysfunction in as much as 45% of patients with AS vs only 8.3% revealed by conventional echocardiography. RV systolic function does not significantly improve early after TAVI while RV-PA coupling does. Patients with lower TAPSE/PASP at baseline have worst LV and RV systolic function as well as larger RA. Patients who improve TAPSE/PASP after TAVI are those with worst diastolic function, RV systolic function and larger RA at baseline.
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