ArticleJMIR research protocols2022
Island Study Linking Aging and Neurodegenerative Disease (ISLAND) Targeting Dementia Risk Reduction: Protocol for a Prospective Web-Based Cohort Study.
Article in JMIR research protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 52 citations in OpenAlex.
- Association of tongue, handgrip, and pinch strength with blood-based phosphorylated-tau 181 in cognitively healthy older adults.GeroScience · 2026Article
- Motor speech markers of Alzheimer's risk.GeroScience · 2026Article
- Hearing Loss and Modifiable Dementia Risk Factors in Adults Aged 50 Years or Older Living in Tasmania, Australia.Australasian journal on ageing · 2026Article
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- Regional and Socioeconomic Disparities in Frailty Across Tasmania: Evidence From Island Study Linking Ageing and Neurodegenerative Disease.Australasian journal on ageing · 2026Article
- Article
- Smartphone self-testing of hand and speech motor functions: a study of reliability and usability in older adults.GeroScience · 2026Article
- Psychosocial hierarchies of modifiable risk for Alzheimer's disease: A networks analysis.PloS one · 2026Article
- Self-testing for symptoms and signs of prodromal alpha-synucleinopathies: results from the Tasmanian ISLAND Sleep Study.GeroScience · 2025Article
- Are We Asking the Right Questions? Sex Specificity of Dream Characteristics in Probable Rapid Eye Movement Sleep Behavior Disorder.Movement disorders clinical practice · 2025Article
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- A comparison of modifiable risk factors for dementia among South Asian migrants and non-migrants aged 50 or older in Tasmania, Australia.BMC public health · 2025Article
- Building healthcare capacity for neurodegenerative disease management in Nigeria: Challenges and opportunities.Journal of public health research · 2025Article
- Feasibility of computerized motor, cognitive and speech tests in the home: Analysis of TAS Test in 2,300 older adults.The journal of prevention of Alzheimer's disease · 2025Article
- Hearing loss, social isolation and depression in participants aged 50 years or over in Tasmania, Australia.Australasian journal on ageing · 2024Article
- Development of a smartphone screening test for preclinical Alzheimer's disease and validation across the dementia continuum.BMC neurology · 2024Article
- Estimating presymptomatic episodic memory impairment using simple hand movement tests: A cross-sectional study of a large sample of older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- ISLAND Campus: a fee-free formal university educational intervention in mid- to later-life to reduce modifiable risk factors for dementia and improve cognition.Frontiers in aging neuroscience · 2024Article
- Article
- An online, public health framework supporting behaviour change to reduce dementia risk: interim results from the ISLAND study linking ageing and neurodegenerative disease.BMC public health · 2023Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUp to 40% of incident dementia is considered attributable to behavioral and lifestyle factors. Given the current lack of medical treatments and the projected increase in dementia prevalence, a focus on prevention through risk reduction is needed.
objectiveWe aim to increase dementia risk knowledge and promote changes in dementia risk behaviors at individual and population levels.
methodsThe Island Study Linking Aging and Neurodegenerative Disease (ISLAND) is a long-term prospective, web-based cohort study with nested interventions that will be conducted over a 10-year period. Target participants (n=10,000) reside in Tasmania and are aged 50 years or over. Survey data on knowledge, attitudes, and behaviors related to modifiable dementia risk factors will be collected annually. After each survey wave, participants will be provided with a personalized dementia risk profile containing guidelines for reducing risk across 9 behavioral and lifestyle domains and with opportunities to engage in educational and behavioral interventions targeting risk reduction. Survey data will be modeled longitudinally with intervention engagement indices, cognitive function indices, and blood-based biomarkers, to measure change in risk over time.
resultsIn the initial 12 months (October 2019 to October 2020), 6410 participants have provided baseline data. The study is ongoing.
conclusionsRecruitment targets are feasible and efforts are ongoing to achieve a representative sample. Findings will inform future public health dementia risk reduction initiatives by showing whether, when, and how dementia risk can be lowered through educational and behavioral interventions, delivered in an uncontrolled real-world context. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/34688.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.