Evidence map›Paper›PMID 35230135›Full record

ArticleThe British journal of radiology2022

Radiation and iodine dose reduced thoraco-abdomino-pelvic dual-energy CT at 40 keV reconstructed with deep learning image reconstruction.

Yoshifumi Noda, Nobuyuki Kawai, Tomotaka Kawamura, Akikazu Kobori, Rena Miyase, Ken Iwashima, Tetsuro Kaga, Toshiharu Miyoshi, Fuminori Hyodo, Hiroki Kato and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07305103 (Defining Dosimetric Reference Levels in Computed Tomography Spectral Scanning), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07305103 active not recruitingnot on this mapstarted 2025, after this paper: background citation

Defining Dosimetric Reference Levels in Computed Tomography Spectral Scanning

TypeobservationalSponsorCentre Hospitalier Universitaire de NīmesRan2025 to 2026Enrolled9,600ConditionsMedical ImagingArmsSpectral ComputedTomography
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Systematic Review on Learning-based Spectral CT.IEEE transactions on radiation and plasma medical sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yoshifumi NodaDepartment of Radiology, Gifu University, Gifu, Japan.
Nobuyuki KawaiDepartment of Radiology, Gifu University, Gifu, Japan.
Tomotaka KawamuraDepartment of Radiology, Gifu University, Gifu, Japan.
Akikazu KoboriDepartment of Radiology, Gifu University, Gifu, Japan.
Rena MiyaseDepartment of Radiology, Gifu University, Gifu, Japan.
Ken IwashimaDepartment of Radiology, Gifu University, Gifu, Japan.
Tetsuro KagaDepartment of Radiology, Gifu University, Gifu, Japan.
Toshiharu MiyoshiDepartment of Radiology Services, Gifu University Hospital, Gifu, Japan.
Fuminori HyodoDepartment of Radiology, Frontier Science for Imaging, Gifu University, Gifu, Japan.
Hiroki KatoDepartment of Radiology, Gifu University, Gifu, Japan.
Masayuki MatsuoDepartment of Radiology, Gifu University, Gifu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the feasibility of a simultaneous reduction of radiation and iodine doses in dual-energy thoraco-abdomino-pelvic CT reconstructed with deep learning image reconstruction (DLIR).

methodsThoraco-abdomino-pelvic CT was prospectively performed in 111 participants; 52 participants underwent a standard-dose single-energy CT with a standard iodine dose (600 mgI/kg; SD group), while 59 underwent a low-dose dual-energy CT with a reduced iodine dose [300 mgI/kg; double low-dose (DLD) group]. CT data were reconstructed with a hybrid iterative reconstruction in the SD group and a high-strength level of DLIR at 40 keV in the DLD group. Two radiologists measured the CT numbers of the descending and abdominal aorta, portal vein, hepatic vein, inferior vena cava, liver, pancreas, spleen, and kidney, and background noise. Two other radiologists assessed diagnostic acceptability using a 5-point scale. The CT dose-index volume (CTDI

resultsThe median CTDI

conclusionVirtual monochromatic images at 40 keV reconstructed with DLIR could achieve half doses of radiation and iodine while maintaining diagnostic image quality. ADVANCES IN KNOWLEDGE: Virtual monochromatic images at 40 keV reconstructed with DLIR algorithm allowed to reduce the doses of radiation and iodine while maintaining diagnostic image quality.

Indexed as

Deep LearningIodineAlgorithmsHumansImage Processing, Computer-AssistedIodidesRadiation DosageRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedIodidesIodine

Identifiers

PMID35230135
PMCPMC10996425

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