Evidence map›Paper›PMID 35229959›Full record

ArticleAddiction biology2022

Hyperbolic discounting rates and risk for problematic alcohol use in youth enrolled in the Adolescent Brain and Cognitive Development study.

Robert J Kohler, Sarah D Lichenstein, Sarah W Yip

Open access · greenAbstract read
In one paragraph

Article in Addiction biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Associations Between Steep Delay Discounting and Punishment Learning.Computational psychiatry (Cambridge, Mass.) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Delay discounting and symptoms of anxiety and depression in adolescents experiencing challenges with managing type 1 diabetes.Children's health care : journal of the Association for the Care of Children's Health · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Robert J KohlerDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-7450-2490
Sarah D LichensteinDepartment of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA.
Sarah W YipDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
Yale University · US

Funding

Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Psychosocial and neurobiological stress and opioid use trajectories following pregnancyR01DA050636 · NIDA · YALE UNIVERSITY · PI RUTHERFORD, HELENA JV, YIP, SARAH · 2020 to 2024
$2.8M
Connectome-based prediction and neurodevelopmental trajectories of alcohol phenotypes across developmentR01AA027553 · NIAAA · YALE UNIVERSITY · PI SCHEINOST, DUSTIN, YIP, SARAH · 2019 to 2022
$1.7M
Connectome-based neuromarkers of problem cannabis useK08DA051667 · NIDA · YALE UNIVERSITY · PI LICHENSTEIN, SARAH D. · 2020 to 2024
$959k
Neural mechanisms of galantamine treatment for cocaine dependenceK01DA039299 · NIDA · YALE UNIVERSITY · PI YIP, SARAH · 2016 to 2020
$905k
Real-time fMRI neurofeedback of large-scale network dynamics in opioid use disorderR21DA049583 · NIDA · YALE UNIVERSITY · PI GARRISON, KATHLEEN A., SCHEINOST, DUSTIN · 2019 to 2020
$461k
NIAAA NIH HHS R01 AA027553NIDA NIH HHS K01 DA039299NIDA NIH HHS K08 DA051667NIDA NIH HHS R01 DA050636NIDA NIH HHS R21 DA049583NIDA NIH HHS T32 DA007238
6 · The paper itself

Abstract

Adolescence is the peak period for the emergence of substance use, which can lead to long-term psychosocial, occupational and interpersonal complications. Ongoing large-scale, longitudinal, consortium initiatives, such as the Adolescent Brain and Cognitive Development (ABCD) study, offer unprecedented opportunities to elucidate key risk factors for problematic substance use in a well-powered sample and to examine how changes in risk factors relate to symptoms across time. Delay discounting has been proposed as a putative risk marker for early substance-use initiation and other forms of psychopathology. However, the extent to which other factors (e.g., socio-economic status and cognitive ability) influence discounting behaviour in young adolescents is not well established. The present study leverages data from the ABCD study (n = 11 045) to assess associations between core demographic and familial variables and delay discounting in youth-operationalized using hyperbolic discounting rates (k)-before the onset of significant psychopathology. Model estimates revealed significant effects of individual difference factors (e.g., sex and socio-economic status) and alcohol risk status (based on family history) on delay discounting. No significant differences were observed in the primary sample when comparing the presence of parent drug problems or prenatal drug exposures. These effects will require replication in later waves of ABCD. Nonetheless, these results provide support for delay discounting as a potential risk marker for problematic alcohol use and demonstrate a relationship between key demographic variables and adolescent discounting behaviour. Further, these results provide an empirical baseline from which developmental trajectories of delay discounting and substance use may be tracked throughout future waves of ABCD.

Indexed as

Delay DiscountingSubstance-Related DisordersAdolescentAlcohol DrinkingBrainCognitionHumansRewardaddictioncomputational modellingdecision-makingdevelopmentinitiationreward

Identifiers

PMID35229959
PMCPMC9289942
OpenAlexW4214613549

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.