SynthesisEuropean journal of cancer care2022
Acceptability of and barriers to human papillomavirus vaccination in China: A systematic review of the Chinese and English scientific literature.
Synthesis in European journal of cancer care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Vaccine Chatbot on HPV Vaccine Awareness and Vaccination for Middle School Girls in China: a Randomized Controlled Trial and Implementation Science Study
Evaluation of a Vaccine Chatbot on HPV Vaccine Confidence and Hesitancy: a Randomized Controlled Trial and Implementation Science Study
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review and thematic synthesis exploring how gay, bisexual and other men who have sex with men (GBMSM) experience HPV and HPV vaccination.Human vaccines & immunotherapeutics · 2025Pooled it
- Acceptability of and barriers to human papillomavirus vaccination in China: A systematic review of the Chinese and English scientific literature.European journal of cancer care · 2022Pooled it
- Trial
- Feasibility and Acceptability of Pay-it-forward in Increasing Uptake of HPV Vaccination among 15- to 18-Year-Old Girls in China: Pilot RCT Results.Cancer prevention research (Philadelphia, Pa.) · 2025Trial
- HPV vaccination intention among unvaccinated international and domestic college students in the U.S.: A cross-sectional survey.Human vaccines & immunotherapeutics · 2026Article
- Association of the HPV vaccination intention‒behavior gap with ehealth literacy and health beliefs among chinese female college students: cross-sectional study.Scientific reports · 2026Article
- HPV vaccination willingness and its determinants among male university students post-approval of male-specific HPV vaccines in China: a large-scale cross-sectional study.BMC public health · 2026Article
- Urban-rural disparities in HPV vaccination knowledge, willingness, and uptake among women in the Tibet autonomous region: a multi-center cross-sectional study.Frontiers in public health · 2026Article
- Human papillomavirus (HPV) and HPV vaccine awareness in Indigenous communities in Northwest Territories, Canada.PloS one · 2026Article
- Promoting HPV vaccination among adolescent girls in low-resource areas of China: A multi-centered qualitative study.Human vaccines & immunotherapeutics · 2025Article
- Exploring the willingness to pay for HPV vaccines and price sensitivity among Chinese college students: the impact of health literacy and vaccine hesitancy.Frontiers in public health · 2025Article
- Article
- Socioeconomic disparities in HPV vaccine uptake: multivariable analysis of vaccination data from Tianjin (2018-2023).Frontiers in public health · 2025Article
- HPV vaccination willingness and behavior among patients with cervical intraepithelial neoplasia in low-resource areas of Western China: a cross-sectional study.Frontiers in public health · 2025Article
- Beyond health: exploring women's socio-cultural motivations for HPV vaccination.International journal of qualitative studies on health and well-being · 2024Article
- Inequities in human papillomavirus vaccination among children aged 9-14 years old under constrained vaccine supply in China.International journal for equity in health · 2024Article
- Between now and later: a mixed methods study of HPV vaccination delay among Chinese caregivers in urban Chengdu, China.BMC public health · 2024Article
- Lower rate of mpox vaccination hesitancy and medical consultation among Chinese men who have sex with men living with HIV in comparison with those living without HIV: A national observational study.Human vaccines & immunotherapeutics · 2023Observational
- The coverage and challenges of increasing uptake of non-National Immunization Program vaccines in China: a scoping review.Infectious diseases of poverty · 2023Article
- Review
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
introductionWidespread adoption of the human papillomavirus (HPV) vaccine will require population acceptance and tailoring of immunisation services to community needs and preferences. We examined peer-reviewed publications on the acceptability of and barriers to the HPV vaccine across China.
methodsWe searched English (MEDLINE, Embase, and Web of Science) and Chinese (CNKI, VIP, Wanfang data) databases between 1 January 2006 and 31 December 2017. We adopted a narrative approach for data synthesis.
resultsWe identified 73 studies. The overall median acceptability of HPV vaccine was 71.8% (Q1-Q3: 58.6%-81%). Low levels of acceptability (<40%) of HPV vaccine were found in eastern regions of China. The largest differences of acceptability were observed between rural western regions (all >90%) and urban eastern regions (all <35%). Despite these regional variations, common barriers to HPV vaccine acceptance were concerns about vaccine safety, uncertainty over vaccine effectiveness, low perceived risk of cervical cancer and the price of the vaccine. The level of willingness to pay for the HPV vaccine (over 153 US dollars) was very low (<7%).
conclusionThe acceptability of and attitudes towards HPV vaccine vary by regions and populations across China. HPV vaccination programmes will need to tailor service delivery as well as information materials to take account of regional concerns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.