SynthesisPediatric dermatology2022
Comparison of lichen sclerosus in boys and girls: A systematic literature review of epidemiology, symptoms, genetic background, risk factors, treatment, and prognosis.
Synthesis in Pediatric dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The Importance of Immunological Disorders in the Pathogenesis of Lichen Sclerosus in Pediatric Patients: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Comparison of lichen sclerosus in boys and girls: A systematic literature review of epidemiology, symptoms, genetic background, risk factors, treatment, and prognosis.Pediatric dermatology · 2022Pooled it
- Sex- and Gender-Related Differences in Pruritus in Dermatological Diseases: Insights into Inflammatory, Autoimmune, and Connective Tissue Disorders.Life (Basel, Switzerland) · 2026Review
- Article
- Genital Disorders in Children: What Does a Biopsy Bring?Dermatopathology (Basel, Switzerland) · 2026Review
- Extragenital Lichen Sclerosus With Vulvar Involvement in a Child: A Clinical and Dermoscopic Perspective.Cureus · 2026Article
- Lichen sclerosus in paediatric patients with phimosis undergoing circumcision.Skin health and disease · 2025Article
- Signs and symptoms of vulval lichen sclerosus in children and adolescents: a scoping review protocol.BMJ open · 2025Article
- Regional Variations in the Incidence of Lichen Sclerosus in Sweden: Insights from a Nationwide Register Study (2001-2021).Journal of clinical medicine · 2024Article
- Possible Role of NRF2 in Cell Response to OZOILE (Stable Ozonides) in Children Affected by Lichen Sclerosus of Foreskin.Current issues in molecular biology · 2024Article
- Lichen Sclerosus-Incidence and Comorbidity: A Nationwide Swedish Register Study.Journal of clinical medicine · 2024Article
- Vulvar Lichen Sclerosus: Navigating Sex Hormone Dynamics and Pioneering Personalized Treatment Paradigm.Journal of personalized medicine · 2024Review
- Lichen sclerosus: The 2023 update.Frontiers in medicine · 2023Review
- First use of cord blood platelet-rich plasma in the treatment of vulvar lichen sclerosus: a preliminary study towards a randomized controlled trial.Blood transfusion = Trasfusione del sangueArticle
- Pediatric lichen sclerosus: a self-limited disease? A long-term follow-up case series.Anais brasileiros de dermatologiaArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStudies concerning pediatric lichen sclerosus are limited, and, to date, there have been no studies comparing the course of lichen sclerosus in boys and girls. We sought to examine all publications on boys and girls with lichen sclerosus and assess and compare epidemiology, symptoms and signs, genetic background, risk factors, treatment, and prognosis.
methodsA systematic search was performed in the Embase, Medline, Cochrane, and Web of Science databases. Inclusion criteria were information on children ages 0-18 years and a clinical or histologic diagnosis of lichen sclerosus. Literature from 1985 to 2021 was reviewed.
resultsA total of 1780 articles were retrieved from the search, of which 90 articles were eligible for inclusion. Boys and girls present similarly on many aspects; nonetheless, treatment and follow-up are approached differently.
conclusionsThough the clinical approach is often different, lichen sclerosus in boys and girls demonstrates many similarities. More research is needed, especially on follow-up, to gain a better understanding of the course of lichen sclerosus and establish an advanced management plan for children.
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