Evidence map›Paper›PMID 35229882›Full record

ArticleThe Australasian journal of dermatology2022

Thalidomide for prevention of camrelizumab-induced reactive cutaneous capillary endothelial proliferation.

Geng Song, Fei-Fei Zhang, Huai-Dong Cheng

Open access · greenAbstract read
In one paragraph

Article in The Australasian journal of dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Geng SongDepartment of Oncology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID https://orcid.org/0000-0001-5649-3025
Fei-Fei ZhangDepartment of Oncology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Huai-Dong ChengDepartment of Oncology, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.
Anhui Medical University · CN

Funding

National Natural Science Foundation of China No. 81872504
6 · The paper itself

Abstract

objectivesThe study evaluated the efficacy of thalidomide in prevention of camrelizumab-induced reactive cutaneous capillary endothelial proliferation (RCCEP).

methodsIn this study, patients treated with camrelizumab plus thalidomide or camrelizumab alone were included. The occurrences, onset time, severity of RCCEP and the adverse effect of thalidomide were analysed.

resultsA total of 19 patients were enrolled. The incidence of RCCEP in thalidomide group (2/9, 22.2%) was significantly lower than that in camrelizumab group (8/10, 80%). The median onset time of RCCEP was 5 weeks and 4 weeks respectively. The adverse events of thalidomide were mild, and no treatment-associated interruption was observed.

conclusionsThalidomide showed a promising in prevention of the RCCEP in patients receiving camrelizumab therapy with an acceptable safety profile.

Indexed as

Antibodies, Monoclonal, HumanizedThalidomideAntineoplastic Combined Chemotherapy ProtocolsCell ProliferationHumansAntibodies, Monoclonal, HumanizedcamrelizumabThalidomidecamrelizumabreactive cutaneous capillary endothelial proliferationthalidomide

Identifiers

PMID35229882
PMCPMC9313837
OpenAlexW4214750719

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.