Evidence map›Paper›PMID 35229839›Full record

ArticlePhysical chemistry chemical physics : PCCP2022

Elastic moduli of normal and cancer cell membranes revealed by molecular dynamics simulations.

Hoang Linh Nguyen, Viet Hoang Man, Mai Suan Li, Philippe Derreumaux, Junmei Wang, Phuong H Nguyen

Open access · greenAbstract read
In one paragraph

Article in Physical chemistry chemical physics : PCCP, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Hoang Linh NguyenInstitute for Computational Science and Technology, SBI Building, Quang Trung Software City, Tan Chanh Hiep Ward, District 12, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0003-4141-1642
Viet Hoang ManDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15213, USA.
Mai Suan LiInstitute for Computational Science and Technology, SBI Building, Quang Trung Software City, Tan Chanh Hiep Ward, District 12, Ho Chi Minh City, Vietnam.ORCID http://orcid.org/0000-0001-7021-7916
Philippe DerreumauxCNRS, Université de Paris, UPR9080, Laboratoire de Biochimie Théorique, Paris, France.
Junmei WangDepartment of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15213, USA.ORCID http://orcid.org/0000-0002-9607-8229
Phuong H NguyenCNRS, Université de Paris, UPR9080, Laboratoire de Biochimie Théorique, Paris, France.ORCID http://orcid.org/0000-0003-1284-967X
Centre National de la Recherche Scientifique · FRInstitute for Computational Science and Technology · VNUniversity of Pittsburgh · US

Funding

Development of novel computational protocols to study amyloid oligomerizationK25AG070277 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAN, VIET HOANG · 2021 to 2025
$736k
NIA NIH HHS K25 AG070277
6 · The paper itself

Abstract

Recent studies indicate that there are mechanical differences between normal cells and cancer cells. Because the cell membrane takes part in a variety of vital processes, we test the hypothesis of whether or not two fundamental alterations in the cell membrane,

Indexed as

Molecular Dynamics SimulationNeoplasmsCell MembraneCholesterolLipid BilayersMembranesCholesterolLipid Bilayers

Identifiers

PMID35229839
PMCPMC8988946
OpenAlexW4213302683

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.