Evidence map›Paper›PMID 35229659›Full record

ArticleJournal of the American Heart Association2022

Temporal Trends in Racial and Ethnic Disparities in Endovascular Therapy in Acute Ischemic Stroke.

Faheem Sheriff, Haolin Xu, Alberto Maud, Vikas Gupta, Anantha Vellipuram, Gregg C Fonarow, Roland A Matsouaka, Ying Xian, Mathew Reeves, Eric E Smith and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  3. Observational
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  18. Racial and Ethnic Disparities in Stroke Reperfusion Therapy in the USA.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Faheem SheriffTexas Tech University Health Sciences Center El Paso TX.ORCID 0000-0002-3875-6175
Haolin XuDuke Clinical Res Inst Durham Durham NC.ORCID 0000-0003-1069-9567
Alberto MaudTexas Tech University Health Sciences Center El Paso TX.
Vikas GuptaTexas Tech University Health Sciences Center El Paso TX.ORCID 0000-0002-4625-7413
Anantha VellipuramTexas Tech University Health Sciences Center El Paso TX.
Gregg C FonarowUCLA Division of CardiologyRonald Reagan-UCLA Medical Center Los Angeles CA.ORCID 0000-0002-3192-8093
Roland A MatsouakaDuke Univ Durham NC.ORCID 0000-0002-0271-5400
Ying XianUniversity of Texas Southwestern Medical Center Dallas TX.ORCID 0000-0002-1237-1162
Mathew ReevesCollege of Human Medicine Michigan State University East Lansing MI.ORCID 0000-0002-8019-6343
Eric E SmithUniversity of Calgary Calgary AB Canada.ORCID 0000-0003-3956-1668
Jeffrey SaverGeffen School of Medicine at UCLA Los Angeles CA.ORCID 0000-0001-9141-2251
Gustavo RodriguezTexas Tech University Health Sciences Center El Paso TX.ORCID 0000-0003-2781-5034
Salvador Cruz-FloresTexas Tech University Health Sciences Center El Paso TX.
Lee H SchwammMass General HospitalHarvard Medical School Boston MA.ORCID 0000-0003-0592-9145
Texas Tech University · USClinical Research Institute · USMassachusetts General Hospital · USMichigan State University · USRonald Reagan UCLA Medical Center · USThe University of Texas Southwestern Medical Center · USUniversity of Calgary · CAUniversity of California, Los Angeles · US

Funding

New England Regional Coordinating Center for the NINDS Stroke Trials Network (StrokeNet)U24NS107243 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ANEESH B SINGHAL · 2018 to 2026
$3.3M
NINDS NIH HHS U24 NS107243
6 · The paper itself

Abstract

Introduction Endovascular therapy (EVT) use increased following clinical trials publication in 2015, but limited data suggest there may be persistent race and ethnicity differences. Methods and Results We included all patients with acute ischemic stroke arriving within 6 hours of last known well and with National Institute of Health Stroke Scale (NIHSS) score ≥6 between April 2012 and June 2019 in the Get With The Guidelines-Stroke database and evaluated the association between race and ethnicity and EVT use and outcomes, comparing the era before versus after 2015. Of 302 965 potentially eligible patients; 42 422 (14%) underwent EVT. Although EVT use increased over time in all racial and ethnic groups, Black patients had reduced odds of EVT use compared with non-Hispanic White (NHW) patients (adjusted odds ratio [aOR] before 2015, 0.68 [0.58‒0.78]; aOR after 2015, 0.83 [0.76‒0.90]). In-hospital mortality/discharge to hospice was less frequent in Black, Hispanic, and Asian patients compared with NHW. Conversely discharge home was more frequent in Hispanic (29.7%; aOR, 1.28 [1.16‒1.42]), Asian (28.2%; aOR, 1.23 [1.05‒1.44]), and Black (29.1%; aOR, 1.08 [1.00‒1.18]) patients compared with NHW (24%). However, at 3 months, functional independence (modified Rankin Scale, 0-2) occurred less frequently in Black (37.5%; aOR, 0.84 [0.75‒0.95]) and Asian (33%; aOR, 0.79 [0.65‒0.98]) patients compared with NHW patients (38.1%). Conclusions In a large cohort of patients treated with EVT, Black versus NHW patient disparities in EVT use have narrowed over time but still exist. Discharge related outcomes were slightly more favorable in racial and ethnic underrepresented groups; 3-month functional outcomes were worse but improved across all groups with time.

Indexed as

Endovascular ProceduresIschemic StrokeStrokeEthnicityHispanic or LatinoHumansTreatment Outcomeendovascular therapyhealth equityischemic strokerace and ethnicity

Identifiers

PMID35229659
PMCPMC9075329
OpenAlexW4214510345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.