Evidence map›Paper›PMID 35229632›Full record

ArticlemBio2022

Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei.

Emilia Jane McLaughlin, Karinna Rubio-Pena, Annick Dujeancourt-Henry, Lucy Glover

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Emilia Jane McLaughlinInstitut Pasteurgrid.428999.7, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.
Karinna Rubio-PenaInstitut Pasteurgrid.428999.7, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.
Annick Dujeancourt-HenryInstitut Pasteurgrid.428999.7, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.
Lucy GloverInstitut Pasteurgrid.428999.7, Université de Paris, Trypanosome Molecular Biology, Department of Parasites and Insect Vectors, Paris, France.ORCID 0000-0001-7191-6890
Institut Pasteur · FR

Funding

Agence Nationale de la Recherche (ANR) VSGREGEC | H2020 | H2020 Priority Excellent Science | H2020 Marie Skłodowska-Curie Actions (MSCA) 665807Fondation pour la Recherche Médicale (FRM) FDT202012010602Institut Pasteur G5 funding
6 · The paper itself

Abstract

In the mammalian host, Trypanosoma brucei is coated in a single-variant surface glycoprotein (VSG) species. Stochastic switching of the expressed

Indexed as

Trypanosoma brucei bruceiTrypanosomiasis, AfricanAnimalsAntigenic VariationGene ConversionHumansMammalsMembrane GlycoproteinsMembrane Glycoproteinsantigenic variationTrypanosoma bruceiVSG

Identifiers

PMID35229632
PMCPMC8941856
OpenAlexW4214480418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.