Evidence map›Paper›PMID 35229491›Full record

ArticlePediatric pulmonology2022

Diagnosis, management, and outcomes of pediatric tracheostomy-associated infections: A scoping review.

John M Morrison, Amir Hassan, Lynn Kysh, Robert A Dudas, Christopher J Russell

Open access · bronzeAbstract readScoping Review
In one paragraph

Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Post-operative tracheitis in the NICU: incidence and risk factors.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  6. Predictors of Frequent Acute Respiratory Infections in Children with Tracheostomies.medRxiv : the preprint server for health sciences · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Equitable Care for Children With a Tracheostomy: Addressing Challenges and Seeking Systemic Solutions.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

John M MorrisonDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-2882-8849
Amir HassanDivision of Hospital Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.
Lynn KyshThe Institute for Nursing and Interprofessional Research, Children's Hospital Los Angeles, Los Angeles, California, USA.
Robert A DudasDepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Christopher J RussellDivision of Hospital Medicine, Children's Hospital Los Angeles, Los Angeles, California, USA.ORCID 0000-0002-5269-7861
Children's Hospital of Los Angeles · USJohns Hopkins University · USUniversity of Southern California · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Mentored Career DevelopmentKL2TR001854 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Elizabeth Rhea Erwin Burner, Amy Elizabeth West · 2016 to 2026
$9.0M
Southern California Clinical and Translational Science InstituteKL2TR000131 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$2.1M
NCATS NIH HHS KL2 TR000131NCATS NIH HHS KL2 TR001854NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855
6 · The paper itself

Abstract

backgroundChildren with tracheostomy are frequently admitted to the hospital for tracheostomy-associated respiratory infections (TRAINs). However, there remains a paucity of evidence to direct the diagnosis, treatment, and prevention of TRAINs. An important first step to addressing this knowledge gap is to synthesize existing data regarding TRAINs to inform current practice and facilitate innovation. DATA SOURCES: We searched PubMed, Embase, Cochrane Library, CINAHL, and Web of Science from inception to October 2020. Original research articles and published abstracts including children and young adults 0-21 years of age with tracheostomy were included. Included studies assessed the clinical definitions of and risk factors for TRAINs, microbiologic epidemiology and colonization of tracheostomies, and treatment and outcomes of TRAINs. DATA SYNTHESIS: Out of 5755 studies identified in the search, 78 full-text studies were included in the final review. A substantial number of studies focused on the detection of specific pathogens in respiratory cultures including Pseudomonas aeruginosa. Several different definitions of TRAIN including clinical, microbiologic, and laboratory testing results were utilized; however, no uniform set of criteria were identified. The few studies focused on treatment and prevention of TRAIN emphasized the role of empiric antimicrobial therapy and the use of inhaled antibiotics.

conclusionsDespite a growing number of research articles studying TRAINs, there is a paucity of prospective interventional trials to guide the diagnosis, treatment, and prevention of respiratory disease in this vulnerable population. Future research should include studies of interventions designed to improve short- and long-term respiratory-related outcomes of children with tracheostomy.

Indexed as

Respiratory Tract InfectionsTracheostomyAnti-Bacterial AgentsChildHumansPostoperative ComplicationsProspective StudiesPseudomonas aeruginosaAnti-Bacterial Agentspediatricspneumoniatracheitistracheostomy

Identifiers

PMID35229491
PMCPMC9313552
OpenAlexW4214641480

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.