Evidence map›Paper›PMID 35229437›Full record

ReviewEnvironmental microbiology2022

Towards standardized and reproducible research in skin microbiomes.

Matti O Ruuskanen, Deepti Vats, Renuka Potbhare, Ameeta RaviKumar, Eveliina Munukka, Richa Ashma, Leo Lahti

Abstract readReview
In one paragraph

Review in Environmental microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Toward the Next Generation of In Silico Modeling of Dynamic Host-Microbiota Interactions in the Skin.JID innovations : skin science from molecules to population health · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Article
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  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Matti O Ruuskanen *Department of Computing, Faculty of Technology, University of Turku, Turku, Finland.ORCID 0000-0003-4221-2880
Deepti Vats *Department of Zoology, Centre of Advanced Study, Savitribai Phule Pune University, Pune, India.
Renuka Potbhare *Department of Zoology, Centre of Advanced Study, Savitribai Phule Pune University, Pune, India.ORCID 0000-0003-3541-8151
Ameeta RaviKumarInstitute of Bioinformatics and Biotechnology, Savitribai Phule Pune University, Pune, India.ORCID 0000-0002-7088-0416
Eveliina MunukkaMicrobiome Biobank, Institute of Biomedicine, University of Turku, Turku, Finland.
Richa AshmaDepartment of Zoology, Centre of Advanced Study, Savitribai Phule Pune University, Pune, India.ORCID 0000-0002-0099-9497
Leo LahtiDepartment of Computing, Faculty of Technology, University of Turku, Turku, Finland.ORCID 0000-0001-5537-637X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin is a complex organ serving a critical role as a barrier and mediator of interactions between the human body and its environment. Recent studies have uncovered how resident microbial communities play a significant role in maintaining the normal healthy function of the skin and the immune system. In turn, numerous host-associated and environmental factors influence these communities' composition and diversity across the cutaneous surface. In addition, specific compositional changes in skin microbiota have also been connected to the development of several chronic diseases. The current era of microbiome research is characterized by its reliance on large data sets of nucleotide sequences produced with high-throughput sequencing of sample-extracted DNA. These approaches have yielded new insights into many previously uncharacterized microbial communities. Application of standardized practices in the study of skin microbial communities could help us understand their complex structures, functional capacities, and health associations and increase the reproducibility of the research. Here, we overview the current research in human skin microbiomes and outline challenges specific to their study. Furthermore, we provide perspectives on recent advances in methods, analytical tools and applications of skin microbiomes in medicine and forensics.

Indexed as

MicrobiotaDNAHigh-Throughput Nucleotide SequencingHumansReproducibility of ResultsSkinDNA

Identifiers

PMID35229437
PMCPMC9790573

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.