SynthesisThe European journal of neuroscience2022
Cortical complexity estimation using fractal dimension: A systematic review of the literature on clinical and nonclinical samples.
Synthesis in The European journal of neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cortical complexity in eating disorders: a systematic review and qualitative synthesis.European archives of psychiatry and clinical neuroscience · 2026Pooled it
- Cortical complexity estimation using fractal dimension: A systematic review of the literature on clinical and nonclinical samples.The European journal of neuroscience · 2022Pooled it
- Structural Brain Changes Are Linked to Clinical and Cognitive Outcomes in Anti-LGI1 Encephalitis.Neurology(R) neuroimmunology & neuroinflammation · 2026Observational
- The geometry of disorder: fractal analysis in psychiatric neuroimaging.European radiology · 2026Article
- Spike dynamics in primate lateral prefrontal cortex during working memory and decision-making: A fractal analysis.iScience · 2026Article
- Texture-Based MRI Analysis Reveals Microstructural Alterations in the Putamen in Bipolar Disorder.Medicina (Kaunas, Lithuania) · 2026Article
- Brain structural morphometry in non-musicians with superior pitch identification ability.Scientific reports · 2026Article
- Quantification and characterization of collagen in experimentally induced wounds treated with different types of platelet-rich plasma gel.Cell and tissue banking · 2026Article
- Association of structural brain changes with cognitive deficits and fatigue in patients with post-COVID-19 condition.Brain communications · 2026Article
- When prediction fails: a computational complexity view of stress.Frontiers in veterinary science · 2026Article
- Physical, cognitive, and psychosocial fatigue are differently related to cortical complexity of superior temporal and frontal brain regions in Crohn's disease.Frontiers in neuroimaging · 2026Article
- Fractal analysis of brain shape formation predicts age and genetic similarity in human newborns.Nature neuroscience · 2026Article
- Fractal Dimension in Healthy Hippocampi and Hippocampi With Mesial Temporal Sclerosis: An Observational Study.Cureus · 2025Article
- Neural correlates of inattention in adults with ADHD.European archives of psychiatry and clinical neuroscience · 2025Article
- Magnetic Resonance Neuroimaging in Amyotrophic Lateral Sclerosis: A Comprehensive Umbrella Review of 18 Studies.Brain sciences · 2025Review
- Morphometric Evidence of a U-Shaped Relationship Between Loss Aversion and Posterior Insular/Somatosensory Cortical Features.Human brain mapping · 2025Article
- Article
- Molecular architecture of the altered cortical complexity in autism.Molecular autism · 2025Article
- Ventricular volume adjustment of brain regions depicts brain changes associated with HIV infection and aging better than intracranial volume adjustment.Frontiers in neurology · 2025Article
- Cortical Morphological Networks Differ Between Gyri and Sulci.Neuroscience bulletin · 2025Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Fractal geometry has recently been proposed as a useful tool for characterizing the complexity of the brain cortex, which is likely to derive from the recurrence of sulci-gyri convolution patterns. The index used to describe the cortical complexity is called fractal dimensional (FD) and was employed by different research exploring the neurobiological correlates of distinct pathological and nonpathological conditions. This review aims to describe the literature on the application of this index, summarize the heterogeneities between studies and inform future research on this topic. Sixty-two studies were included in the systematic review. The main research lines concern neurodevelopment, aging and the neurobiology of specific psychiatric and neurological disorders. Overall, the included papers indicate that cortical complexity is likely to reduce during aging and in various pathological processes affecting the brain. Nevertheless, the high heterogeneity between studies strongly prevents the possibility of drawing conclusions. Further research considering this index besides other morphological values is needed to better clarify the role of FD in characterizing the cortical structure.
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