Evidence map›Paper›PMID 35229168›Full record

ArticleLangenbeck's archives of surgery2022

Pure laparoscopic major liver resection after yttrium

Daniel Aliseda, Pablo Martí-Cruchaga, Gabriel Zozaya, Alberto Benito, Luis Lopez-Olaondo, Macarena Rodríguez-Fraile, José I Bilbao, Francisco Hidalgo, Mercedes Iñarrairaegui, Rubén Ciria and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Langenbeck's archives of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. LaparoscopicAnnals of surgical treatment and research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Daniel AlisedaHPB and Liver Transplant Unit, Department of General Surgery, Clinica Universidad de Navarra, University of Navarra, Av. Pío XII, 36, 31008, Pamplona, Spain.
Pablo Martí-CruchagaHPB and Liver Transplant Unit, Department of General Surgery, Clinica Universidad de Navarra, University of Navarra, Av. Pío XII, 36, 31008, Pamplona, Spain.
Gabriel ZozayaHPB and Liver Transplant Unit, Department of General Surgery, Clinica Universidad de Navarra, University of Navarra, Av. Pío XII, 36, 31008, Pamplona, Spain.
Alberto BenitoInstitute of Health Research of Navarra (IdisNA), Pamplona, Spain.
Luis Lopez-OlaondoInstitute of Health Research of Navarra (IdisNA), Pamplona, Spain.
Macarena Rodríguez-FraileInstitute of Health Research of Navarra (IdisNA), Pamplona, Spain.
José I BilbaoInstitute of Health Research of Navarra (IdisNA), Pamplona, Spain.
Francisco HidalgoInstitute of Health Research of Navarra (IdisNA), Pamplona, Spain.
Mercedes IñarrairaeguiInstitute of Health Research of Navarra (IdisNA), Pamplona, Spain.
Rubén CiriaUnit of Hepatobiliary Surgery and Liver Transplantation, IMIBIC, University Hospital Reina Sofía, University of Cordoba, Cordoba, Spain.
Fernando PardoHPB and Liver Transplant Unit, Department of General Surgery, Clinica Universidad de Navarra, University of Navarra, Av. Pío XII, 36, 31008, Pamplona, Spain.
Bruno SangroInstitute of Health Research of Navarra (IdisNA), Pamplona, Spain.
Fernando RotellarHPB and Liver Transplant Unit, Department of General Surgery, Clinica Universidad de Navarra, University of Navarra, Av. Pío XII, 36, 31008, Pamplona, Spain. frotellar@unav.es.ORCID http://orcid.org/0000-0002-6557-0712
Navarre Institute of Health Research · ESClinica Universidad de Navarra · ESInstituto Maimónides de Investigación Biomédica de Córdoba · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiver surgery after radioembolization (RE) entails highly demanding and challenging procedures due to the frequent combination of large tumors, severe RE-related adhesions, and the necessity of conducting major hepatectomies. Laparoscopic liver resection (LLR) and its associated advantages could provide benefits, as yet unreported, to these patients. The current study evaluated feasibility, morbidity, mortality, and survival outcomes for major laparoscopic liver resection after radioembolization. MATERIAL AND

methodsIn this retrospective, single-center study patients diagnosed with hepatocellular carcinoma, intrahepatic cholangiocarcinoma or metastases from colorectal cancer undergoing major laparoscopic hepatectomy after RE were identified from institutional databases. They were matched (1:2) on several pre-operative characteristics to a group of patients that underwent major LLR for the same malignancies during the same period but without previous RE.

resultsFrom March 2011 to November 2020, 9 patients underwent a major LLR after RE. No differences were observed in intraoperative blood loss (50 vs. 150 ml; p = 0.621), operative time (478 vs. 407 min; p = 0.135) or pedicle clamping time (90.5 vs 74 min; p = 0.133) between the post-RE LLR and the matched group. Similarly, no differences were observed on hospital stay (median 3 vs. 4 days; p = 0.300), Clavien-Dindo ≥ III complications (2 vs. 1 cases; p = 0.250), specific liver morbidity (1 vs. 1 case p = 1.000), or 90 day mortality (0 vs. 0; p = 1.000).

conclusionThe laparoscopic approach for post radioembolization patients may be a feasible and safe procedure with excellent surgical and oncological outcomes and meets the current standards for laparoscopic liver resections. Further studies with larger series are needed to confirm the results herein presented.

Indexed as

Bile Duct NeoplasmsCarcinoma, HepatocellularLaparoscopyLiver NeoplasmsBile Ducts, IntrahepaticFeasibility StudiesHepatectomyHumansLength of StayPostoperative ComplicationsRetrospective StudiesYttriumYttriumColorectal liver metastasesHepatocellular carcinomaIntrahepatic cholangiocarcinomaLaparoscopic liver resectionRadioembolization

Identifiers

PMID35229168
PMCPMC9151566
OpenAlexW4214590296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.