ArticleAlzheimer's & dementia (New York, N. Y.)2022
The impact of hearing impairment and hearing aid use on progression to mild cognitive impairment in cognitively healthy adults: An observational cohort study.
Article in Alzheimer's & dementia (New York, N. Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06955494 (The Effect of the "Empowerment Network for Auditory-Cognitive Training), which is not on this map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of the "Empowerment Network for Auditory-Cognitive Training (ENACT) Program" on Auditory Perception and Function, Cognitive Function and Health-related Quality of Life of Persons Living With Mild Cognitive Impairment
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Relationship Between Clusters of Multimorbidity and Dementia Risk: A Systematic Review.International journal of geriatric psychiatry · 2025Pooled it
- Effect of hearing aids on cognitive functions in middle-aged and older adults with hearing loss: A systematic review and meta-analysis.Frontiers in aging neuroscience · 2022Pooled it
- Knowledge, Attitudes and Practices of Audiologists in India Towards Audiological Care of Individuals with Cognitive Impairments-A Preliminary Exploratory Study.Audiology research · 2026Article
- Hearing Loss, Cognitive Decline, and Dementia: Clinical Intersections.Audiology research · 2026Review
- Hearing aid effectiveness and probable dementia risk across 33 countries: A pooled analysis of seven cohorts.Cell reports. Medicine · 2026Article
- A sensorimotor function construct to assess mild cognitive impairment risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Building bridges: the integral presence of audiologists and speech-language pathologists in comprehensive interprofessional primary care teams.Primary health care research & development · 2026Article
- Dementia and hearing loss: from risk to mechanisms and management.Frontiers in dementia · 2026Review
- Identifying predictors of speech-in-noise perception in older adults with hearing impairment: the key role of working memory.BMC geriatrics · 2025Article
- Hearing loss and cognitive function among older adults in 18 high-income countries: Moderating and Mediating factors.Research square · 2025Article
- Relationship between hearing thresholds and cognitive function in hearing aid non-users and long-term users post-midlife.npj aging · 2025Article
- Results from AD-HEARING (ADherence to and adjustment of HEARING aids in clinical routine care as preventive dementia strategy): a prospective 6-month follow-up study on cognition and psychological well-being.Frontiers in psychiatry · 2025Article
- Beyond the auditory system: cognitive implications of age-related hearing loss.Frontiers in aging neuroscience · 2025Review
- Working memory capacity moderates the effect of hearing aid experience on phonological processing performance.Frontiers in neuroscience · 2025Article
- Depressive symptoms mediate the relationship between cognitive reserve and cognitive performance in middle-aged and older Chinese adults: evidence from population-based and clinical PET cohorts including cognitively normal and cognitively impaired participants.Frontiers in aging neuroscience · 2025Article
- Aging-associated sensory decline and Alzheimer's disease.Molecular neurodegeneration · 2024Review
- From Mild Cognitive Impairment to Dementia: The Impact of Comorbid Conditions on Disease Conversion.Biomedicines · 2024Article
- Subjective hearing loss is not associated with an increased risk of Alzheimer's disease dementia.Heliyon · 2024Article
- Wearable Technologies for Healthy Ageing: Prospects, Challenges, and Ethical Considerations.The Journal of frailty & aging · 2024Article
- Sensorineural hearing loss and cognitive impairment: three hypotheses.Frontiers in aging neuroscience · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
introductionWe assessed the association of self-reported hearing impairment and hearing aid use with cognitive decline and progression to mild cognitive impairment (MCI).
methodsWe used a large referral-based cohort of 4358 participants obtained from the National Alzheimer's Coordinating Center. The standard covariate-adjusted Cox proportional hazards model, the marginal structural Cox model with inverse probability weighting, standardized Kaplan-Meier curves, and linear mixed-effects models were applied to test the hypotheses.
resultsHearing impairment was associated with increased risk of MCI (standardized hazard ratio [HR] 2.58, 95% confidence interval [CI: 1.73 to 3.84], DISCUSSION: Use of hearing aids may help mitigate cognitive decline associated with hearing loss.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.