Evidence map›Paper›PMID 35229019›Full record

ArticleAlzheimer's & dementia (New York, N. Y.)2022

Lack of association between bridging integrator 1 (

Jolien Schaeverbeke, Emma S Luckett, Silvy Gabel, Mariska Reinartz, Steffi De Meyer, Isabelle Cleynen, Kristel Sleegers, Christine Van Broeckhoven, Guy Bormans, Kim Serdons and 4 more

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (New York, N. Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Exploring the association betweenFrontiers in neurology · 2025
    Article
  3. Review
  4. Lack of association between bridging integrator 1 (Alzheimer's & dementia (New York, N. Y.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Jolien SchaeverbekeDepartment of Neurosciences, Laboratory for Cognitive Neurology Leuven Brain Institute, KU Leuven Leuven Belgium.
Emma S LuckettDepartment of Neurosciences, Laboratory for Cognitive Neurology Leuven Brain Institute, KU Leuven Leuven Belgium.
Silvy GabelDepartment of Neurosciences, Laboratory for Cognitive Neurology Leuven Brain Institute, KU Leuven Leuven Belgium.
Mariska ReinartzDepartment of Neurosciences, Laboratory for Cognitive Neurology Leuven Brain Institute, KU Leuven Leuven Belgium.
Steffi De MeyerDepartment of Neurosciences, Laboratory for Molecular Neurobiomarker Research Leuven Brain Institute, KU Leuven Leuven Belgium.
Isabelle CleynenLaboratory for Complex Genetics KU Leuven Leuven Belgium.
Kristel SleegersVIB-UAntwerp Center for Molecular Neurology Antwerp Belgium.
Christine Van BroeckhovenVIB-UAntwerp Center for Molecular Neurology Antwerp Belgium.
Guy BormansLaboratory for Radiopharmaceutical Research KU Leuven Leuven Belgium.
Kim SerdonsDivision of Nuclear Medicine UZ Leuven Leuven Belgium.
Koen Van LaereDivision of Nuclear Medicine UZ Leuven Leuven Belgium.
Patrick DupontDepartment of Neurosciences, Laboratory for Cognitive Neurology Leuven Brain Institute, KU Leuven Leuven Belgium.
Rik VandenbergheDepartment of Neurosciences, Laboratory for Cognitive Neurology Leuven Brain Institute, KU Leuven Leuven Belgium.
and the Alzheimer's Disease Neuroimaging Initiative**
VIB-KU Leuven Center for Brain & Disease Research · BEAllen Institute for Brain Science · USUniversity of Antwerp · BECenter for Human Genetics · USKU Leuven · BEUniversitair Ziekenhuis Leuven · BEVIB-KU Leuven Center for Microbiology · BE

Funding

Alzheimer's Disease Neuroimaging Initiative - SupplementU01AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI WEINER, MICHAEL W · 2004 to 2015
$121.0M
NIA NIH HHS U01 AG024904
6 · The paper itself

Abstract

introductionThe bridging integrator 1(

methodsThe

resultsForty-four percent of F-PACK participants were DISCUSSION: We could not confirm the association between

Indexed as

[18F]AV1451ADNIAPOEBIN1 rs744373F‐PACKMCIPETpreclinical Alzheimer's disease

Identifiers

PMID35229019
PMCPMC8864573
OpenAlexW4213315898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.