ArticleInternational journal of general medicine2022
Value of Neutrophil:Lymphocyte Ratio Combined with Sequential Organ Failure Assessment Score in Assessing the Prognosis of Sepsis Patients.
Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
- Prognostic Value of 48-Hour Biomarker Reassessment Beyond Admission SOFA for 28-Day Mortality in Sepsis.Diagnostics (Basel, Switzerland) · 2026Article
- Early ΔNLR Outperforms Baseline Inflammatory Markers in Predicting Short-Term Outcomes in Sepsis.Diagnostics (Basel, Switzerland) · 2026Article
- Integrating serum ferritin and neutrophil-to-lymphocyte ratio with Sequential Organ Failure Assessment score improves mortality prediction in sepsis.World journal of methodology · 2026Article
- Neutrophil to lymphocyte ratio (NLR) and short-term mortality risk in elderly acute medical patients admitted to a University Hospital Emergency Department: comment.Internal and emergency medicine · 2025Article
- Dynamic neutrophil-to-lymphocyte-platelet ratio trajectories predict 30-day and 1-year mortality in sepsis: a retrospective cohort study based on MIMIC-IV 2.2.BMC infectious diseases · 2025Article
- Prognostic utility of procalcitonin and lactate clearance for in-hospital mortality in sepsis.Frontiers in medicine · 2025Article
- Study of the Role of C-reactive Protein/Procalcitonin Ratio as a Prognostic Tool in ICU Patients with Sepsis: A Prospective Observational Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Development of a Predictive Nomogram for Sepsis in Patients with Urolithiasis-Related Obstructive Pyelonephritis.Medicina (Kaunas, Lithuania) · 2024Article
- Predictive Value of Inflammatory Markers NLR, PLR, APRI, SII, and Liver Function Tests in Systemic Inflammatory Response Syndrome Detection in Full-Term Newborns.Children (Basel, Switzerland) · 2024Article
- Blood neutrophil to lymphocyte ratio is associated with 90-day mortality and 60-day readmission in Gram negative bacteremia: a multi-center cohort study.BMC infectious diseases · 2024Article
- C-reactive protein and procalcitonin during course of sepsis and septic shock.Irish journal of medical science · 2024Article
- Severe Acute Bronchial Asthma with Sepsis: Determining the Status of Biomarkers in the Diagnosis of the Disease.Diagnostics (Basel, Switzerland) · 2023Review
- Factors associated with left ventricular diastolic dysfunction in patients with septic shock.European journal of medical research · 2022Article
- Correlation and Prognostic Assessment of Low T3 Syndrome and Norepinephrine Dosage for Patients with Sepsis: A Retrospective Single-Center (Cohort) Study.International journal of general medicine · 2022Article
- Quick Sequential Organ Failure Assessment Score, Lactate, and Neutrophil-Lymphocyte Ratio Help in Diagnosis and Mortality Prediction during Golden Hour of Sepsis in Emergency Department.Journal of emergencies, trauma, and shockArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe aimed to evaluate risk factors and assessment values in patients with sepsis and to explore a method of improving prognosis-prediction efficiency for patients with sepsis.
methodsPatients with sepsis admitted to the Emergency Medicine Clinical Research Center, Beijing Chao-Yang Hospital, Capital Medical University from January 2020 to December 2020 were enrolled. Demographic data of patients and laboratory values at admission were collected. Sequential organ failure assessment (SOFA) and acute physiology and chronic health evaluation II (APACHE II) scores were calculated within 24 hours of admission and logistic regression used to analyze risk factors of death within 28 days, as well as the combined predictor of SOFA score and neutrophil:lymphocyte ratio (NLR). Predicted values of various indicators for 28-day mortality in sepsis patients were analyzed using receiver-operating characteristic curves.
resultsA total of 302 patients were included in this study, of whom 64 (21.2%) died. Age, Pct, CRP, Lac, NLR (OR 1.054, 95% CI 1.032-1.076), SOFA score (OR 1.434, 95% CI 1.293-1.591), APACHE II score (OR 1.231, 95% CI 1.166-1.300), and NLR combined with SOFA (SOFA+NLR×0.149: OR 1.455, 95% CI 1.318-1.605) were risk factors of 28-day mortality in sepsis patients, and areas under the curve of NLR combined with SOFA score were significantly higher than each of NLR and SOFA scores and similar to APACHE II scores. The sensitivity and specificity of NLR combined with SOFA and APACHE II scores to predict the 28-day prognosis of sepsis patients were better than the other indicators.
conclusionNLR combined with SOFA was a risk factor of the death of sepsis patients and its predictive efficacy similar to that of the APACHE II score, which is superior to other predictive indices.
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