Evidence map›Paper›PMID 35228715›Full record

ArticleCommunications biology2022

Neuronal-glial communication perturbations in murine SOD1

Michael MacLean, Raquel López-Díez, Carolina Vasquez, Paul F Gugger, Ann Marie Schmidt

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

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  14. Defining the molecular identity and morphology ofbioRxiv : the preprint server for biology · 2023
    Article
  15. Article
  16. Publicly availableFrontiers in neuroscience · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Michael MacLeanDiabetes Research Program, Department of Medicine, New York University Grossman School of Medicine, New York, NY, 10016, USA.
Raquel López-DíezDiabetes Research Program, Department of Medicine, New York University Grossman School of Medicine, New York, NY, 10016, USA.
Carolina VasquezDiabetes Research Program, Department of Medicine, New York University Grossman School of Medicine, New York, NY, 10016, USA.
Paul F GuggerDiabetes Research Program, Department of Medicine, New York University Grossman School of Medicine, New York, NY, 10016, USA.
Ann Marie SchmidtDiabetes Research Program, Department of Medicine, New York University Grossman School of Medicine, New York, NY, 10016, USA. AnnMarie.Schmidt@nyulangone.org.ORCID 0000-0001-8902-070X
New York University · US

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
RAGE: A Potential Contributor to Neuroinflammation in Amyotrophic Lateral SclerosisF31NS120424 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MACLEAN, MICHAEL · 2020 to 2020
$43k
NCI NIH HHS P30 CA016087NINDS NIH HHS F31 NS120424United States Department of Defense | United States Army | Army Medical Command | Congressionally Directed Medical Research Programs (CDMRP) W81XWH-17-1-0346
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is an incurable disease characterized by proteinaceous aggregate accumulation and neuroinflammation culminating in rapidly progressive lower and upper motor neuron death. To interrogate cell-intrinsic and inter-cell type perturbations in ALS, single-nucleus RNA sequencing was performed on the lumbar spinal cord in the murine ALS model SOD1

Indexed as

Amyotrophic Lateral SclerosisCell CommunicationMotor NeuronsNeurogliaSpinal CordSuperoxide Dismutase-1AnimalsDisease Models, AnimalMiceSod1 protein, mouseSuperoxide Dismutase-1

Identifiers

PMID35228715
PMCPMC8885678
OpenAlexW4214738157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.