Evidence map›Paper›PMID 35228711›Full record

ArticleBone marrow transplantation2022

Gilteritinib enhances graft-versus-leukemia effects against FLT3-ITD mutant leukemia after allogeneic hematopoietic stem cell transplantation.

Zixuan Zhang, Yuta Hasegawa, Daigo Hashimoto, Hajime Senjo, Ryo Kikuchi, Xuanzhong Chen, Kazuki Yoneda, Tomoko Sekiguchi, Tatsuya Kawase, Hirofumi Tsuzuki and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  7. Review
  8. Article
  9. Case Report: Pediatric AML withFrontiers in oncology · 2025
    Article
  10. Article
  11. Review
  12. Maintenance strategies for relapse prevention and treatment.Hematology. American Society of Hematology. Education Program · 2024
    Review
  13. Article
  14. Review
  15. Article
  16. Hematopoietic Stem Cells and Their Niche in Bone Marrow.International journal of molecular sciences · 2024
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Zixuan Zhang *Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Yuta Hasegawa *Department of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Daigo HashimotoDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan. D5hash@pop.med.hokudai.ac.jp.ORCID 0000-0001-9489-9704
Hajime SenjoDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.ORCID 0000-0002-5382-5167
Ryo KikuchiDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Xuanzhong ChenDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Kazuki YonedaDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Tomoko SekiguchiDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Tatsuya KawaseDrug Discovery Research, Astellas Pharma Inc., Tsukuba, Japan.
Hirofumi TsuzukiDrug Discovery Research, Astellas Pharma Inc., Tsukuba, Japan.
Takashi IshioDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Takahide AraDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.ORCID 0000-0001-9609-3202
Hiroyuki OhigashiDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Masao NakagawaDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.
Takanori TeshimaDepartment of Hematology, Hokkaido University Faculty of Medicine, Graduate School of Medicine, Sapporo, 060-8638, Japan.ORCID 0000-0002-0941-271X
Hokkaido University · JPAstellas Pharma (Japan) · JPSapporo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic hematopoietic stem cell transplantation (allo-SCT) is a potentially curative therapy for FLT3 internal tandem duplication mutant (FLT3-ITD

Indexed as

Graft vs Leukemia EffectHematopoietic Stem Cell TransplantationLeukemia, Myeloid, AcuteAniline CompoundsAnimalsCD8-Positive T-Lymphocytesfms-Like Tyrosine Kinase 3Interleukin-15MiceMutationPyrazinesTransplantation, HomologousAniline CompoundsFlt3 protein, mousefms-Like Tyrosine Kinase 3gilteritinibInterleukin-15Pyrazines

Identifiers

PMID35228711
OpenAlexW4214589398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.