Evidence map›Paper›PMID 35228649›Full record

ArticleCommunications biology2022

Dietary salt with nitric oxide deficiency induces nocturnal polyuria in mice via hyperactivation of intrarenal angiotensin II-SPAK-NCC pathway.

Y Sekii, H Kiuchi, K Takezawa, T Imanaka, S Kuribayashi, K Okada, Y Inagaki, N Ueda, S Fukuhara, R Imamura and 2 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Y SekiiDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.ORCID 0000-0002-6204-5103
H KiuchiDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan. kiuchi@uro.med.osaka-u.ac.jp.ORCID 0000-0002-8085-2144
K TakezawaDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.ORCID 0000-0003-1137-1846
T ImanakaDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.ORCID 0000-0001-5403-5362
S KuribayashiDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.
K OkadaDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.ORCID 0000-0002-0338-4842
Y InagakiDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.ORCID 0000-0001-9406-2269
N UedaDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.ORCID 0000-0001-9131-2867
S FukuharaDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.ORCID 0000-0003-1336-4316
R ImamuraDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.
H NegoroDepartment of Urology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
N NonomuraDepartment of Urology,Graduate School of Medicine, Osaka University, Suita, Japan.
The University of Osaka · JPUniversity of Tsukuba · JP

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) JP19K18582
6 · The paper itself

Abstract

Nocturnal polyuria is the most frequent cause of nocturia, a common disease associated with a compromised quality of life and increased mortality. Its pathogenesis is complex, and the detailed underlying mechanism remains unknown. Herein, we report that concomitant intake of a high-salt diet and reduced nitric oxide (NO) production achieved through N

Indexed as

Angiotensin IINocturiaAnimalsMiceMice, KnockoutNitric OxidePhosphorylationPolyuriaProtein Serine-Threonine KinasesQuality of LifeSodium Chloride, DietaryAngiotensin IINitric OxideProtein Serine-Threonine KinasesSodium Chloride, Dietary

Identifiers

PMID35228649
PMCPMC8885931
OpenAlexW4214549416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.