Evidence map›Paper›PMID 35228629›Full record

Observational studyScientific reports2022

Hemodynamic variations in arterial wave reflection associated with the application of increasing levels of PEEP in healthy subjects.

Jacopo Belfiore, Etrusca Brogi, Niccolo Nicolini, Davide Deffenu, Francesco Forfori, Carlo Palombo

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06123039 (Use of Heart-lung Interaction Parameters to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP During Invasive Mechanical Ventilation in the Operating Room), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06123039 completednot on this mapstarted 2023, after this paper: background citation

Use of Heart-lung Interaction Parameters to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP During Invasive Mechanical Ventilation in the Operating Room

TypeobservationalSponsorHospital Universitario La FeRan2023 to 2025Enrolled72ConditionsAnesthesia, Perioperative/Postoperative Complications, Hypovolemia, Haemodynamic InstabilityArmsTidal Volume Challenge, Recruitment maneuver obtaining individualised PEEP
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jacopo BelfioreDivision of Anaesthesia and Intensive Care, Department of Surgical, Medical, Molecular and Critical Care Area, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy.
Etrusca BrogiDivision of Anaesthesia and Intensive Care, Department of Surgical, Medical, Molecular and Critical Care Area, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy. etruscabrogi@gmail.com.
Niccolo NicoliniDivision of Anaesthesia and Intensive Care, Department of Surgical, Medical, Molecular and Critical Care Area, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy.
Davide DeffenuDivision of Anaesthesia and Intensive Care, Department of Surgical, Medical, Molecular and Critical Care Area, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy.
Francesco ForforiDivision of Anaesthesia and Intensive Care, Department of Surgical, Medical, Molecular and Critical Care Area, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy.
Carlo PalomboDivision of Anaesthesia and Intensive Care, Department of Surgical, Medical, Molecular and Critical Care Area, University of Pisa, Via Paradisa 2, 56124, Pisa, Italy.
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Positive end-expiratory pressure (PEEP) may affect arterial wave propagation and reflection, thus influencing ventricular loading conditions. The aim of the study was to investigate the hemodynamic variations in arterial wave reflection (i.e., wave reflection time, augmentation index, left ventricular ejection time, diastolic time, SEVR) associated with the application of increasing levels of PEEP in healthy subjects. We conducted a prospective observational study. Study population was selected from students and staff. Pulse contour wave analysis was performed from the right carotid artery during stepwise increase in PEEP levels (from 0 cmH

Indexed as

HemodynamicsPositive-Pressure RespirationHealthy VolunteersHeart VentriclesHumansSystole

Identifiers

PMID35228629
PMCPMC8885708
OpenAlexW4214911528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.