Evidence map›Paper›PMID 35228551›Full record

Observational studyScientific reports2022

Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016.

Ai Kurogi, Daisuke Onozuka, Akihito Hagihara, Kunihiro Nishimura, Akiko Kada, Manabu Hasegawa, Takahiro Higashi, Takanari Kitazono, Tsuyoshi Ohta, Nobuyuki Sakai and 5 more

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ai KurogiDepartment of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Daisuke OnozukaDepartment of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Akihito HagiharaDepartment of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Kunihiro NishimuraDepartment of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center, Suita, Japan.
Akiko KadaDepartment of Clinical Research Planning and Management, Clinical Research Center, National Hospital Organization Nagoya Medical Centre, Nagoya, Japan.
Manabu HasegawaImmunization Office, Health Service Division, Health Service Bureau, Ministry of Health, Labor and Welfare, Tokyo, Japan.
Takahiro HigashiDivision of Health Services Research, Center for Cancer Control and Information Services, National Cancer Center, Tokyo, Japan.
Takanari KitazonoDepartment of Medicine and Clinical Science, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan.
Tsuyoshi OhtaDepartment of Neurosurgery, National Cerebral and Cardiovascular Center, Suita, Japan.
Nobuyuki SakaiDepartment of Neurosurgery, Kobe City Medical Centre General Hospital, Kobe, Japan.
Hajime AraiDepartment of Neurosurgery, Juntendo University School of Medicine, Tokyo, Japan.
Susumu MiyamotoDepartment of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Tetsuya SakamotoDepartment of Emergency Medicine, Teikyo University School of Medicine, Tokyo, Japan.
Koji IiharaDepartment of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. kiihara@ncvc.go.jp.
J-ASPECT Study Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine whether increasing thrombectomy-capable hospitals with moderate comprehensive stroke center (CSC) capabilities is a valid alternative to centralization of those with high CSC capabilities. This retrospective, nationwide, observational study used data from the J-ASPECT database linked to national emergency medical service (EMS) records, captured during 2013-2016. We compared the influence of mechanical thrombectomy (MT) use, the CSC score, and the total EMS response time on the modified Rankin Scale score at discharge among patients with acute ischemic stroke transported by ambulance, in phases I (2013-2014, 1461 patients) and II (2015-2016, 3259 patients). We used ordinal logistic regression analyses to analyze outcomes. From phase I to II, MTs increased from 2.7 to 5.5%, and full-time endovascular physicians per hospital decreased. The CSC score and EMS response time remained unchanged. In phase I, higher CSC scores were associated with better outcomes (1-point increase, odds ratio [95% confidence interval]: 0.951 [0.915-0.989]) and longer EMS response time was associated with worse outcomes (1-min increase, 1.007 [1.001-1.013]). In phase II, neither influenced the outcomes. During the transitional shortage of thrombectomy-capable hospitals, increasing hospitals with moderate CSC scores may increase nationwide access to MT, improving outcomes.

Indexed as

Brain IschemiaEmergency Medical ServicesIschemic StrokeStrokeHospitalsHumansJapanRetrospective StudiesThrombectomyTreatment Outcome

Identifiers

PMID35228551
PMCPMC8885934

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.