Evidence map›Paper›PMID 35228431›Full record

ArticleInternal medicine (Tokyo, Japan)2022

TAFRO Syndrome That Responded to Prednisolone-only Treatment: Evaluating Changes in IL-6.

Hiroyuki Suzuki, Tomoya Sano, Yasumasa Shimasaki, Maki Yamaguchi, Tatsuya Ide, Teruko Arinaga-Hino, Reiichiro Kuwahara, Keisuke Amano, Koichi Oshima, Koji Nagafuji and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Hiroyuki SuzukiDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
Tomoya SanoDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
Yasumasa ShimasakiDepartment of Pathology, Kurume University School of Medicine, Japan.
Maki YamaguchiDivision of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Japan.
Tatsuya IdeDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
Teruko Arinaga-HinoDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
Reiichiro KuwaharaDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
Keisuke AmanoDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
Koichi OshimaDepartment of Pathology, Kurume University School of Medicine, Japan.
Koji NagafujiDivision of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Japan.
Hiroaki IdaDivision of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Japan.
Hironori KogaDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
Takuji TorimuraDivision of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Japan.
Kurume University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly (TAFRO) syndrome is a systemic inflammatory disorder characterized by the above-mentioned symptoms. Because of the similarity in phenotypes between TAFRO syndrome and decompensated liver cirrhosis, an accurate diagnosis is often difficult. We herein report a 62-year-old Japanese patient with TAFRO syndrome who was misdiagnosed with intractable ascites associated with liver cirrhosis. Improvement of symptoms after treatment with prednisolone was associated with interleukin-6 rather than C-reactive protein. The pathogenesis of TAFRO syndrome, which has similar clinical manifestations to liver cirrhosis, remains unclear, and our findings may help elucidate the concept of this condition.

Indexed as

Castleman DiseaseInterleukin-6C-Reactive ProteinEdemaHumansLiver CirrhosisPrednisoloneReticulinC-Reactive ProteinInterleukin-6PrednisoloneReticulinCastleman's diseaseglomeruloid hemangiomaIL-6intractable ascitesTAFRO syndrome

Identifiers

PMID35228431
PMCPMC9593160
OpenAlexW4214543504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.