Evidence map›Paper›PMID 35228425›Full record

ArticleInternal medicine (Tokyo, Japan)2022

Repeated Brain Magnetic Resonance Imaging Provides Clues for the Diagnosis of Autoimmune Glial Fibrillary Acid Protein Astrocytopathy.

Takahiro Natori, Toko Fukao, Tsubasa Watanabe, Takafumi Kurita, Takanori Hata, Akio Kimura, Kazumasa Shindo, Takayoshi Shimohata, Yoshihisa Takiyama

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Takahiro NatoriDepartment of Neurology, University of Yamanashi Hospital, Japan.
Toko FukaoDepartment of Neurology, University of Yamanashi Hospital, Japan.
Tsubasa WatanabeDepartment of Neurology, University of Yamanashi Hospital, Japan.
Takafumi KuritaDepartment of Neurology, University of Yamanashi Hospital, Japan.
Takanori HataDepartment of Neurology, University of Yamanashi Hospital, Japan.
Akio KimuraDepartment of Neurology, Gifu University Hospital, Japan.
Kazumasa ShindoDepartment of Neurology, University of Yamanashi Hospital, Japan.
Takayoshi ShimohataDepartment of Neurology, Gifu University Hospital, Japan.
Yoshihisa TakiyamaDepartment of Neurology, University of Yamanashi Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a 47-year-old man with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) revealed by periventricular radial linear enhancement on repeated brain magnetic resonance imaging (MRI). He presented with a history of headache and a fever followed by somnolence and worsening of consciousness. On admission (16 days from the onset), although lymphocytic pleocytosis and hypoglycorrhachia in the cerebrospinal fluid (CSF) were noted, initial brain MRI demonstrated non-specific findings. At 30 days from the onset, repeated brain MRI revealed characteristic findings of GFAP-A, and we detected anti-GFAP antibodies in the CSF. Thus, repeated brain MRI provides clues for the diagnosis of GFAP-A.

Indexed as

AstrocytesBrainAutoantibodiesGlial Fibrillary Acidic ProteinHumansMagnetic Resonance ImagingMaleMiddle AgedAutoantibodiesGlial Fibrillary Acidic Proteinautoimmune glial fibrillary acid protein astrocytopathy (GFAP-A)meningoencephalitisMRIperiventricular radial gadolinium enhancement

Identifiers

PMID35228425
PMCPMC9593140

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.