Evidence map›Paper›PMID 35228228›Full record

ArticleBMJ case reports2022

Non-gestational uterine choriocarcinoma inside a leiomyoma: importance of early suspicion in prognosis.

Filipa Mendes Coutinho, Sofia Raposo, Teresa Carvalho, Rita Sousa

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Filipa Mendes CoutinhoGynecology Department, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal filipa.mendes.coutinho@gmail.com.ORCID http://orcid.org/0000-0003-3950-6327
Sofia RaposoGynaecology, Francisco Gentil Portuguese Institute for Oncology of Coimbra, Coimbra, Portugal.
Teresa CarvalhoOncology, Francisco Gentil Portuguese Institute for Oncology of Coimbra, Coimbra, Portugal.
Rita SousaGynaecology, Francisco Gentil Portuguese Institute for Oncology of Coimbra, Coimbra, Portugal.
Instituto Português de Oncologia de Coimbra Francisco Gentil · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine choriocarcinoma is a trophoblastic neoplasm most commonly related to pregnancy. However, there are already cases of non-gestational uterine choriocarcinoma (NGC) described in literature. The difficult diagnosis may delay treatment and threaten patient survival. We report the case of a 37-year-old patient presenting with abnormal haemorrhage and moderate levels of beta-human chorionic gonadotropin (β-hCG). As imaging exams did not show any suspicious site for the origin, choriocarcinoma was not considered so the treatment was delayed. Anatomopathological diagnosis was given both from the surgical sample of hysterectomy and from a skin lesion. The lesion was discovered inside a myoma. At this point, β-hCG levels were substantially high and she presented with respiratory distress due to pulmonary metastasis. The patient was transferred to an intensive care unit and underwent mechanical ventilation as well as life-saving chemotherapy. At 10 months after diagnosis, she is well and in remission. The delay from not suspecting the diagnosis was almost fatal for the patient.

Indexed as

ChoriocarcinomaLeiomyomaUterine NeoplasmsAdultChorionic Gonadotropin, beta Subunit, HumanFemaleHumansPregnancyPrognosisChorionic Gonadotropin, beta Subunit, Humanadult intensive carecancer interventioncancer - see oncologycarcinogenesisgynaecology and fertilityobstetrics

Identifiers

PMID35228228
PMCPMC8886367
OpenAlexW4214494160

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.