Evidence map›Paper›PMID 35228036›Full record

ReviewBiophysical chemistry2022

Structural aspects of the MHC expression control system.

Grady Nash, Bhaskar Paidimuddala, Liman Zhang

Open access · greenAbstract readReview
In one paragraph

Review in Biophysical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Grady NashDepartment of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR 97239, USA.
Bhaskar PaidimuddalaDepartment of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR 97239, USA.
Liman ZhangDepartment of Chemical Physiology and Biochemistry, Oregon Health and Science University, Portland, OR 97239, USA. Electronic address: zhanglim@ohsu.edu.
Oregon Health & Science University · US

Funding

Elucidating the Structural Mechanisms of NAIP Receptors in Bacterial Detection and Inflammasome ActivationR01AI165580 · NIAID · VAN ANDEL RESEARCH INSTITUTE · PI Liman Zhang · 2022 to 2026
$2.1M
Structural and Mechanistic Elucidation of NAIP/NLRC4 Inflammasomes in Innate ImmunityR00AI137300 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI ZHANG, LIMAN · 2020 to 2021
$550k
Structural and Mechanistic Elucidation of NAIP/NLRC4 Inflammasomes in Innate ImmunityK99AI137300 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI ZHANG, LIMAN · 2018 to 2019
$232k
NIAID NIH HHS K99 AI137300NIAID NIH HHS R00 AI137300NIAID NIH HHS R01 AI165580
6 · The paper itself

Abstract

The major histocompatibility complex (MHC) spans innate and adaptive immunity by presenting antigenic peptides to CD4

Indexed as

Gene Expression RegulationTrans-ActivatorsCD8-Positive T-LymphocytesMajor Histocompatibility ComplexTranscription FactorsTrans-ActivatorsTranscription FactorsCIITAMHC enhanceosomeNLRNLRC5ProteinsStructural biologyTranscription factors

Identifiers

PMID35228036
PMCPMC8941990
OpenAlexW4213072876

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.