Evidence map›Paper›PMID 35227961›Full record

ArticleGeneral hospital psychiatry

Risk of severe COVID-19 infection in individuals with severe mental disorders, substance use disorders, and common mental disorders.

A Sörberg Wallin, A Ohlis, C Dalman, J Ahlen

Open access · hybridAbstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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  5. Potential Risk Factors to COVID-19 Severity: Comparison of SARS-CoV-2 Delta- and Omicron-Dominant Periods.International journal of environmental research and public health · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A Sörberg WallinCenter for Epidemiology and Community Medicine, Health Care Services, Stockholm County, Sweden; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
A OhlisCenter for Epidemiology and Community Medicine, Health Care Services, Stockholm County, Sweden; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
C DalmanCenter for Epidemiology and Community Medicine, Health Care Services, Stockholm County, Sweden; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.
J AhlenCenter for Epidemiology and Community Medicine, Health Care Services, Stockholm County, Sweden; Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden. Electronic address: johan.ahlen@ki.se.
Stockholm County Council · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the risk of severe COVID-19 in individuals with severe mental disorders, substance use disorders, and common mental disorders in the total adult population of Region Stockholm (N = 1,516,270), and to explore possible underlying mechanisms to the increased risk.

methodsIn this prospective cohort study, we examined the risk of hospitalization and treatment in an intensive care unit (ICU) with COVID-19, and death from COVID-19 for individuals with mental disorders. Associations were step by step adjusted for (1) sociodemographic/economic factors, (2) indicators of virus exposure, (3) somatic conditions, and (4) psychopharmacological treatment.

resultsIn model 1 (adjusted for age, sex and living in a care home for elderly people), people with a mental disorder had increased risks for inpatient care (HR = 1.5), ICU care (HR = 1.5), and mortality (HR = 1.4) from COVID-19. There was an increased risk of dying from COVID-19 in all subgroups of mental disorders, particularly in people with a severe mental disorder (HR = 1.9). Different covariates had different effects on the association depending on the outcome and on sex, age, or psychiatric diagnosis of the participants.

conclusionPeople with mental disorders have an increased risk of severe COVID-19, including mortality. The increased risk was partly explained by the examined covariates.

Indexed as

COVID-19Mental DisordersSubstance-Related DisordersAdultAgedHumansProspective StudiesRisk FactorsSARS-CoV-2Common mental disordersCOVID-19Severe mental disordersSubstance-related disorders

Identifiers

PMID35227961
PMCPMC8863313
OpenAlexW4212898042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.