Evidence map›Paper›PMID 35227793›Full record

ArticleAmerican journal of infection control2022

Containment of a carbapenem-resistant Acinetobacter baumannii complex outbreak in a COVID-19 intensive care unit.

Paula Eckardt, Kelsi Canavan, Rachel Guran, Elizabeth George, Nancimae Miller, Dianeysis H Avendano, Myeongji Kim, Khaled Himed, Karen Heidi Gonzalez Ramirez

Open access · bronzeAbstract read
In one paragraph

Article in American journal of infection control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Active surveillance cultures and cohorting for carbapenem-resistantInfection control and hospital epidemiology · 2026
    Article
  3. Article
  4. The epidemiology of gram-negative bacteremia in Lebanon: a study in four hospitals.Annals of clinical microbiology and antimicrobials · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Synergistic combination of carvedilol, amlodipine, amitriptyline, and antibiotics as an alternative treatment approach for the susceptible and multidrug-resistant A. baumannii infections via drug repurposing.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2023
    Article
  9. Antimicrobial stewardship in the intensive care unit.Journal of intensive medicine · 2023
    Review
  10. Article
  11. Article
  12. Review
  13. Is It Possible to Eradicate Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2022
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Paula EckardtDivision of Infectious Diseases, Infection Control, Memorial Healthcare System, Hollywood, FL.
Kelsi CanavanInfection Prevention, Memorial Hospital Miramar, Miramar, FL.
Rachel GuranEpidemiology and Infection Prevention, Memorial Healthcare System, Hollywood, FL. Electronic address: rguran@mhs.net.
Elizabeth GeorgeMicrobiology Laboratory, Memorial Healthcare System, Hollywood, FL.
Nancimae MillerMicrobiology and Molecular Infectious Disease Laboratory, Memorial Healthcare System, Hollywood, FL.
Dianeysis H AvendanoPharmacy, Memorial Hospital Miramar, FL.
Myeongji KimGraduate Medical Education, Memorial Healthcare System, Hollywood, FL.
Khaled HimedGraduate Medical Education, Memorial Healthcare System, Hollywood, FL.
Karen Heidi Gonzalez RamirezDepartment of Epidemiology, Robert Stempel College of Public Health & Social Work, Florida International University, Miami, FL.
Memorial Healthcare System · USFlorida International University · USMemorial Hospital · USSan Diego Miramar College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA carbapenem-resistant Acinetobacter baumannii outbreak in the COVID intensive care unit of a community hospital was contained using multidrug resistant organism guidelines. The purpose of this study is to report on an outbreak investigation and containment strategy that was used, and to discuss prevention strategy.

methodsA multidisciplinary approach contained the spread of infection. Strategies implemented included consultation with experts, screening, and reversal of personal protective equipment conservation. Ensuring infection control best practices are maintained remain important efforts to reduce the spread of multidrug resistant organisms.

resultsFive patients with carbapenem-resistant Acinetobacter baumannii were identified from routine clinical cultures within one week and one patient was identified from active surveillance cultures. DISCUSSION: Personal protective equipment conservation, strategies to prevent health care personnel exposure, and patient surge staffing protocols may have increased the likelihood of multidrug resistant organism transmission. Environmental and behavioral infection control regulations with effective administrative guidance, active surveillance cultures, and antimicrobial stewardship are critical to prevent future outbreaks.

conclusionsAfter outbreak containment strategies were implemented, no additional patients were identified with carbapenem-resistant Acinetobacter baumannii. Conventional infection prevention and control strategies were re-instituted. A multidisciplinary approach with continued focus on hand hygiene, environmental cleaning, and correct use of personal protective equipment needs to be put in place to successfully contain and prevent the spread of carbapenem resistant infections.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsCOVID-19Cross InfectionAnti-Bacterial AgentsCarbapenemsDisease OutbreaksDrug Resistance, Multiple, BacterialHumansIntensive Care UnitsAnti-Bacterial AgentsCarbapenemsAcinetobacter baumanniiAntimicrobial resistanceContainmentCOVIDInfection controlInfection preventionMDROOutbreakPPE

Identifiers

PMID35227793
PMCPMC8881223
OpenAlexW4214717570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.