Evidence map›Paper›PMID 35227503›Full record

ArticleThe American journal of cardiology2022

Implications of COVID-19 Vaccination on Hospital Encounters and Outcomes.

Brian C Case, Benjamin Rosenfeld, Corey Shea, Hank Rappaport, Cheng Zhang, Giorgio A Medranda, Lowell F Satler, Itsik Ben-Dor, Hayder Hashim, Toby Rogers and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. The impact of the coronavirus pandemic on patients hospitalized due to acute coronary syndrome.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Brian C CaseSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Benjamin RosenfeldSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Corey SheaSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Hank RappaportSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Cheng ZhangSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Giorgio A MedrandaSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Lowell F SatlerSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Itsik Ben-DorSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Hayder HashimSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia.
Toby RogersSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia; Cardiovascular Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Ron WaksmanSection of Interventional Cardiology, MedStar Washington Hospital Center, Washington, District of Columbia. Electronic address: ron.waksman@medstar.net.
MedStar Washington Hospital Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adverse events, including cardiac involvement, after vaccination for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported. We sought to evaluate trends of hospital encounters for vaccine recipients before and after vaccination. We analyzed patients who received the coronavirus disease 2019 (COVID-19) vaccine in the MedStar Health system (11 hospitals in Washington, District of Columbia and Maryland) from December 2020 through August 2021. We then compared hospital encounters (emergency department visits) of patients 60 days before a vaccine dose and 30 days after a vaccine dose, along with encounters related to the SARS-CoV-2 infection itself. The cohort included 5,217 patients who were vaccinated against COVID-19. Our analysis revealed a total of 6,751 emergency department visits, and we divided this total into 3 cohorts: fully vaccinated (n = 1,779), in vaccination window (n = 1,420), and before vaccination (n = 3,552). We found no significant association between vaccination and rate of presentation for acute coronary syndrome, pericarditis, myocarditis, heart failure, conduction abnormality, or noncardiac conditions. Further, encounters for complications related to SARS-CoV-2 infection decreased significantly from those before vaccination (5.4%) to those in vaccination window (4.2%) to those who were fully vaccinated (1.6%). These findings were consistent when all vaccinated encounters were combined into 1 cohort (fully vaccinated + in vaccination window). In conclusion, our analysis suggests that there is no significant association of COVID-19 vaccination with the rate of hospital encounters for cardiac disease, including acute coronary syndrome, pericarditis, myocarditis, congestive heart failure, and conduction abnormality. Further, administration of the vaccine resulted in a significant decrease in hospital encounters for SARS-CoV-2 infections and associated complications.

Indexed as

Acute Coronary SyndromeCOVID-19Heart FailureMyocarditisPericarditisCOVID-19 VaccinesHospitalsHumansSARS-CoV-2VaccinationCOVID-19 Vaccines

Identifiers

PMID35227503
PMCPMC8881227
OpenAlexW4214671733

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.