ReviewBMC veterinary research2022
Basics for the potential use of saliva to evaluate stress, inflammation, immune system, and redox homeostasis in pigs.
Review in BMC veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 104 citations in OpenAlex.
- Investigating the Association Between Salivary Profiles, Production-Related Variables, and Daily Lying Time in Dairy Cows: A Pilot Study.Animals : an open access journal from MDPI · 2026Article
- The Salivary Microbiota-Host Nexus: Unraveling Opportunities for Non-Invasive Monitoring of Health and Productivity in Farm Animals.Animals : an open access journal from MDPI · 2026Review
- Salivary responses to an experimental activation of the HPA axis in pigs: Effects of ACTH on analytes related to stress, immune system, inflammation, redox status and metabolism.Veterinary and animal science · 2026Article
- Regular outdoor access decreases stress with positive effects on the health of growing pigs raised on a conventional farm.Scientific reports · 2026Article
- Thermal imaging: A potential tool for early detection of tail lesions in pigs?Animal welfare (South Mimms, England) · 2026Article
- Animal Welfare-Friendly Noninvasive Oral Fluid in Swine Diagnostics: Current Applications in Disease Monitoring, Key Challenges and Future Directions.Veterinary medicine international · 2026Review
- Effect of Preweaning Socialization on Postweaning Biomarkers of Stress, Inflammation, Immunity and Metabolism in Saliva and Serum of Iberian Piglets.Animals : an open access journal from MDPI · 2025Article
- Fecal intestinal inflammatory biomarkers in piglets: analytical validation, homogeneity and stability studies.Veterinary and animal science · 2025Article
- Changes in saliva and serum analytes in domestic pigs and wild boar experimentally infected with African swine fever virus.Veterinary research · 2025Article
- Effect of age and disease on saliva and serum biomarkers of stress, inflammation, immunity, redox and general health status in pigs.Scientific reports · 2025Article
- Precision Livestock Farming Applied to Swine Farms-A Systematic Literature Review.Animals : an open access journal from MDPI · 2025Review
- First report on whole saliva profiling of Landlly pigs for stress, inflammation, immunity, and systemic homeostasis appraisal: a pilot study.Veterinary research communications · 2025Article
- Article
- Measurement of Oro-Cecal Transit Time in LPS-Treated Pigs Fed High and Low Fiber Diets Using the Lactose-Journal of agricultural and food chemistry · 2025Article
- Understanding the Impact of Social Stress on Serum Metabolome and Saliva Biomarkers in Growing-Finishing Pigs.Animals : an open access journal from MDPI · 2025Article
- Assessing salivary cortisol and testosterone as non-invasive biomarkers for GnRH-immunocastration efficiency in heavy pigs.BMC veterinary research · 2025Article
- Changes of Cytokines in Saliva of Pigs withVeterinary sciences · 2025Article
- Oxytocin in horse saliva: validation of a highly sensitive assay and a pilot report about changes in equine gastric ulcer syndrome.BMC veterinary research · 2025Article
- Recent Advances in Biosensor Technologies for Meat Production Chain.Foods (Basel, Switzerland) · 2025Review
- Use of Saliva Analytes as a Predictive Model to Detect Diseases in the Pig: A Pilot Study.Metabolites · 2025Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 1 institution in 1 country.
Funding
Abstract
The use of saliva as a biological sample has many advantages, being especially relevant in pigs where the blood collection is highly stressful and painful, both for the animal and the staff in charge of the sampling. Currently one of the main uses of saliva is for diagnosis and detection of infectious diseases, but the saliva can also be used to measure biomarkers that can provide information of stress, inflammation, immune response and redox homeostasis. This review will be focused on the analytes that can be used for such evaluations. Emphasis will be given in providing data of practical use about their physiological basis, how they can be measured, and their interpretation. In addition, some general rules regarding sampling and saliva storage are provided and the concept of sialochemistry will be addressed. There is still a need for more data and knowledge for most of these biomarkers to optimize their use, application, and interpretation. However, this review provides updated data to illustrate that besides the detection of pathogens in saliva, additional interesting applicative information regarding pigs´ welfare and health can be obtained from this fluid. Information that can potentially be applied to other animal species as well as to humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.