Evidence map›Paper›PMID 35227236›Full record

SynthesisBMC cancer2022

The efficacy and safety of Iodine-131-metaiodobenzylguanidine therapy in patients with neuroblastoma: a meta-analysis.

Huihui He, Qiaoling Xu, Chunjing Yu

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Advances in Radioligand Theranostics in Oncology.Molecular diagnosis & therapy · 2024
    Review
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Huihui HeDepartment of Nuclear Medicine, Affiliated Hospital of Jiangnan University, Wuxi, China.
Qiaoling XuDepartment of Nuclear Medicine, Affiliated Hospital of Jiangnan University, Wuxi, China.
Chunjing YuDepartment of Nuclear Medicine, Affiliated Hospital of Jiangnan University, Wuxi, China. ycjwxd1978@jiangnan.edu.cn.
Wuxi Fourth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveNeuroblastoma is a common extracranial solid tumor of childhood. Recently, multiple treatments have been practiced including Iodine-131-metaiodobenzylguanidine radiation (

methodsMedline, EMBASE database and the Cochrane Library were searched for relevant studies. Eligible studies utilizing

resultsA total of 26 clinical trials including 883 patients were analyzed. The pooled rates of objective response, stable disease, progressive disease, and minor response of

conclusion

Indexed as

3-IodobenzylguanidineAntineoplastic Combined Chemotherapy ProtocolsChild, PreschoolFemaleHumansInfantIodine RadioisotopesMaleNeuroblastomaNeuroendocrine TumorsNeutropeniaSurvival RateTreatment Outcome3-IodobenzylguanidineIodine-131Iodine Radioisotopes131I-MIBGClinical trialsMeta-analysisNeuroblastomaNeuroendocrine tumor

Identifiers

PMID35227236
PMCPMC8883646
OpenAlexW4214686374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.