ArticleTurkish journal of pharmaceutical sciences2022
Novel Indole Derivative as the First P-glycoprotein Inhibitor from the Skin of Indian Toad
Article in Turkish journal of pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 2 citations in OpenAlex.
- Development of heterocyclic derivatives as P-glycoprotein inhibitors against multidrug resistance: pharmacological activities, structure-activity relationship and target (2020-2024).RSC medicinal chemistry · 2025Review
- Toad venom-derived bufadienolides and their therapeutic application in prostate cancers: Current status and future directions.Frontiers in chemistry · 2023Review
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
Objectives: To study the inhibitory effect of novel indole derivative (NID) from Indian toad skin Materials and Methods: Dried Indian toad skin was used to isolate NID with column chromatography, and its structure was elucidated by infrared spectra, Results: The NID has shown increased clear permeability P Conclusion: Many compounds were isolated from the Indian toad skin. This NID was not reported earlier. Results demonstrate NID increased the oral bioavailability of DIG significantly. The isolated NID from Indian toad skin proved as a potent P-gp inhibitor in both
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